Purpose of review The aim of this review is to address and summarize some key issues and recent insights into the hemodynamic support of the trauma patient related to fluid administration. Recent findings Colloids are not superior to crystalloids in treating hypovolemia in the trauma patient and show no survival benefit. Furthermore, several adverse effects (renal failure, bleeding complications and anaphylaxis) have been reported with the use of artificial colloids. Hypertonic saline is effective and well tolerated in the treatment of hypovolemic shock and traumatic brain injury. Potential benefits are reduced fluid requirements and immune modulation. Resuscitation strategies should depend on the type of injury (penetrating vs. blunt; concomitant brain injury). Excessive fluid resuscitation, which can cause acute respiratory distress syndrome, abdominal compartment syndrome and brain edema, should be avoided. Dynamic parameters to guide volume therapy are probably more reliable than static parameters and minimally invasive techniques to monitor the microcirculation are becoming more important to determine the endpoints of resuscitation. Summary Hemodynamic support is an early goal in the treatment of the trauma patient. The use of crystalloids is currently recommended in trauma resuscitation. The amount of fluid we give should be tailored to the individual trauma patient in which clear endpoints of resuscitation are of vital importance to maximize the chances of survival.
机构:
Emergency Medicine,Alborz University of Medical SciencesEmergency Medicine,Alborz University of Medical Sciences
Koorosh Ahmadi
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Mohammad Sedaghat
Mahdi Safdarian
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5th Year Medical Student,Tehran University of Medical SciencesEmergency Medicine,Alborz University of Medical Sciences
Mahdi Safdarian
Amir Masoud Hashemian
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Emergency Medicine,Mashhad University of Medical SciencesEmergency Medicine,Alborz University of Medical Sciences
Amir Masoud Hashemian
Zahra Nezamdoust
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Department of Ophthalmology,Medical Researcher in Private Practice
6. General Practitioner,Medical Researcher in Private Practice
7. Sina TrauEmergency Medicine,Alborz University of Medical Sciences
Zahra Nezamdoust
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Mohammad Vaseie
Vafa Rahimi-Movaghar
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机构:Emergency Medicine,Alborz University of Medical Sciences
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Univ Arizona, Dept Pharm Practice & Sci, Coll Pharm, 1295 N Martin Ave,POB 210202, Tucson, AZ 85721 USAUniv Arizona, Dept Pharm Practice & Sci, Coll Pharm, 1295 N Martin Ave,POB 210202, Tucson, AZ 85721 USA
Erstad, Brian L.
Barletta, Jeffrey F.
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Midwestern Univ, Dept Pharm Practice, Coll Pharm, 19555 N 59th Ave, Glendale, AZ 85308 USAUniv Arizona, Dept Pharm Practice & Sci, Coll Pharm, 1295 N Martin Ave,POB 210202, Tucson, AZ 85721 USA
机构:
Harvard Univ, Massachusetts Gen Hosp, Sch Med, Div Trauma Emergency Surg & Surg Crit Care, Boston, MA 02114 USAHarvard Univ, Massachusetts Gen Hosp, Sch Med, Div Trauma Emergency Surg & Surg Crit Care, Boston, MA 02114 USA
Ramly, Elie
Kaafarani, Haytham M. A.
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Harvard Univ, Massachusetts Gen Hosp, Sch Med, Div Trauma Emergency Surg & Surg Crit Care, Boston, MA 02114 USAHarvard Univ, Massachusetts Gen Hosp, Sch Med, Div Trauma Emergency Surg & Surg Crit Care, Boston, MA 02114 USA
Kaafarani, Haytham M. A.
Velmahos, George C.
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Harvard Univ, Massachusetts Gen Hosp, Sch Med, Div Trauma Emergency Surg & Surg Crit Care, Boston, MA 02114 USAHarvard Univ, Massachusetts Gen Hosp, Sch Med, Div Trauma Emergency Surg & Surg Crit Care, Boston, MA 02114 USA