Flavopiridol-induced apoptosis proceeds via a mitochondrial dependent pathway in human leukemia cells and circumvents Bcl-2-mediated resistance.

被引：0
|
作者：
Decker, RH
Grant, S
机构：
[1] Virginia Commonwealth Univ, Med Coll Virginia, Dept Biochem, Richmond, VA 23298 USA
[2] Virginia Commonwealth Univ, Med Coll Virginia, Div Hematol & Oncol, Richmond, VA 23298 USA
来源：
BLOOD | 2000年 / 96卷 / 11期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
411
引用
收藏
页码：96A / 96A
页数：1
相关论文
共 50 条
  • [21] The BH3-only protein BimL overrides Bcl-2-mediated apoptosis resistance in melanoma cells
    Ploetz, Michael
    Gillissen, Bernhard
    Quast, Sandra-Annika
    Berger, Anja
    Daniel, Peter T.
    Eberle, Juergen
    CANCER LETTERS, 2013, 335 (01) : 100 - 108
  • [22] Small molecule XIAP inhibitors enhance TRAIL- or anticancer drug-induced apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance
    Fakler, M.
    Loeder, S.
    Vogler, M.
    Jeremias, I.
    Debatin, K. M.
    Fulda, S.
    EJC SUPPLEMENTS, 2008, 6 (12): : 87 - 87
  • [23] The cyclin-dependent kinase inhibitor flavopiridol induces apoptosis in human leukemia cells (U937) through the mitochondrial rather than the receptor-mediated pathway
    Decker, RH
    Dai, Y
    Grant, S
    CELL DEATH AND DIFFERENTIATION, 2001, 8 (07): : 715 - 724
  • [24] The BH3-only protein BimL overrides Bcl-2-mediated apoptosis resistance in melanoma cells
    Ploetz, M.
    Gillissen, B.
    Quast, S.
    Berger, A.
    Daniel, P. T.
    Eberle, J.
    EXPERIMENTAL DERMATOLOGY, 2014, 23 (03) : E47 - E47
  • [25] The cyclin-dependent kinase inhibitor flavopiridol induces apoptosis in human leukemia cells (U937) through the mitochondrial rather than the receptor-mediated pathway
    R H Decker
    Y Dai
    S Grant
    Cell Death & Differentiation, 2001, 8 : 715 - 724
  • [26] PIPOXOLAN INDUCES APOPTOSIS OF HUMAN U937 LEUKEMIA CELLS VIA MITOCHONDRIAL-MEDIATED PATHWAY
    Tsai, Huei-Yann
    Yang, Jai-Sing
    Chen, Yuh-Fung
    ANTICANCER RESEARCH, 2008, 28 (5C) : 3522 - 3522
  • [27] Inhibition of glutathione synthesis overcomes Bcl-2-mediated topoisomerase inhibitor resistance and induces nonapoptotic cell death via mitochondrial-independent pathway
    Yoshida, Akira
    Takemura, Haruyuki
    Inoue, Hitoshi
    Miyashita, Toshiyuki
    Ueda, Takanori
    CANCER RESEARCH, 2006, 66 (11) : 5772 - 5780
  • [28] AGFD 149-Mycotoxin patulin induces apoptosis via a mitochondrial-dependent pathway in human leukemia cells
    Liu, Biing-Hui
    Wu, Ting-Shuan
    Yu, Feng-Yih
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 236
  • [29] Cisplatin overcomes Bcl-2-mediated resistance to apoptosis via preferential engagement of Bak: critical role of Noxa-mediated lipid peroxidation
    Kutuk, Ozgur
    Arisan, Elif Damla
    Tezil, Tugsan
    Shoshan, Maria C.
    Basaga, Huveyda
    CARCINOGENESIS, 2009, 30 (09) : 1517 - 1527
  • [30] BNIP3/Bcl-2-mediated apoptosis induced by cyclic tensile stretch in human cartilage endplate-derived stem cells
    Yuan, Chao
    Pu, Luqiao
    He, Zhiliang
    Wang, Jian
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 15 (01) : 235 - 241
12345