The clinical value of squamous cell carcinoma antigen in patients irradiated for locally advanced cancer of the head and neck

被引：0
|
作者：
Micke, O
Bruns, F
Schäfer, U
Horst, E
Büntzel, J
Willich, N
机构：
[1] Univ Klinikum Munster, Klin & Poliklin Strahlentherapie Radioonkol, D-48129 Munster, Germany
[2] Sudharz Krankenhaus Nordhausen GmbH, HNO Klin, D-99734 Nordhausen, Germany
来源：
ANTICANCER RESEARCH | 2003年 / 23卷 / 2A期
关键词：
SCC; squamous cell carcinoma antigen; head and neck cancer; radiochemotherapy; radiotherapy;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Purpose: This study examines the value of squamous cell cancer (SCC) antigen in patients irradiated for locally advanced cancer of the head and neck. Materials and Methods: In 20 patients (group A) treated with radiochemotherapy and in 20 patients (group B) receiving postoperative it-radiation serum SCC values were investigated. Results: The pretreatment SCC level was 1.6 ng/ml in group A and 1.3 ng/ml in group B. In group A 15 % had elevated serum SCC levels above the cut-off level. In group B there were 10 %. During follow-up (median 20 months),. 10 patients in group A and 8 in group B suffered from a recurrent or progressing disease. Of these 20 % in group A and 12.5 % in group B had elevated SCC levels. Conclusion: Our results suggest that, in the described patient groups, SCC is probably of low value for tumor diagnosis and follow-up.
引用
收藏
页码：907 / 911
页数：5
相关论文
共 50 条
  • [21] Erratum to: Fibroblast growth factor 2 is of prognostic value for patients with locally advanced squamous cell carcinoma of the head and neck
    D. Rades
    N.D. Seibold
    M.P. Gebhard
    F. Noack
    K.L. Bruchhage
    S.E. Schild
    Strahlentherapie und Onkologie, 2014, 190 : 323 - 323
  • [22] Prognostic value of human papillomavirus and squamous cell carcinoma antigen in head and neck squamous cell carcinoma
    Deng, Zeyi
    Hasegawa, Masahiro
    Yamashita, Yukashi
    Matayoshi, Sen
    Kiyuna, Asanori
    Agena, Shinya
    Uehara, Takayuki
    Maeda, Hiroyuki
    Suzuki, Mikio
    CANCER SCIENCE, 2012, 103 (12) : 2127 - 2134
  • [23] Accelerated fractionation and concurrent carboplatin in patients with locally advanced squamous cell carcinoma of the head and neck
    Hartley, A. G.
    Sanghera, P.
    Wong, D.
    Glaholm, J.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2008, 72 (01): : S380 - S380
  • [24] Cisplatin versus Carboplatin in Radiochemotherapy for Patients with locally advanced Head and Neck Squamous Cell Carcinoma
    Nassif, S.
    Wichmann, J.
    Christiansen, H.
    Steinmann, D.
    STRAHLENTHERAPIE UND ONKOLOGIE, 2020, 196 (SUPPL 1) : S129 - S129
  • [25] Investigating the impact of treatment on geriatric patients with locally advanced head and neck squamous cell carcinoma
    Liu, Y. T.
    Chen, S-Y.
    Liang, H-K. T.
    Chen, J. P.
    ANNALS OF ONCOLOGY, 2023, 34 : S1614 - S1614
  • [26] Definitive Radiotherapy in Locally Advanced Head and Neck Squamous Cell Cancer with Clinical Extranodal Extension
    Jyotiman Nath
    Gautam Sarma
    Biswajit Samra
    Mouchumee Bhattacharyya
    Apurba Kumar Kalita
    Indian Journal of Otolaryngology and Head & Neck Surgery, 2023, 75 : 3519 - 3529
  • [27] Definitive Radiotherapy in Locally Advanced Head and Neck Squamous Cell Cancer with Clinical Extranodal Extension
    Nath, Jyotiman
    Sarma, Gautam
    Samra, Biswajit
    Bhattacharyya, Mouchumee
    Kalita, Apurba Kumar
    INDIAN JOURNAL OF OTOLARYNGOLOGY AND HEAD & NECK SURGERY, 2023, 75 (04) : 3519 - 3529
  • [28] Weekly cisplatin with radiotherapy for locally advanced head and neck squamous cell carcinoma
    Sautois, Brieuc
    Schroeder, Helene
    Martin, Marie
    Piret, Pascal
    Demez, Pierre
    Bouchain, Olivier
    Mutijima, Eugene
    Moreau, Pierre
    JOURNAL OF BUON, 2016, 21 (04): : 979 - 988
  • [29] Concurrent radiotherapy and chemotherapy for locally advanced squamous cell carcinoma of the head and neck
    Ali, Elsayed M.
    Abdelraheem, Ahmad G.
    HEAD & NECK ONCOLOGY, 2011, 3
  • [30] Toxicity of Cetuximab in Locally Advanced Head and Neck Squamous Cell Carcinoma Treatment
    Torres, S.
    Sargento, I.
    Ferreira, M.
    Oliveira, J. O. A. O.
    EUROPEAN JOURNAL OF CANCER, 2011, 47 : S552 - S552
12345