Comparative analysis of immunophenotypic methods for the assessment of minimal residual disease in hairy cell leukemia

被引:0
|
作者
Bengiò, R [1 ]
Narbaitz, MI [1 ]
Sarmiento, MA [1 ]
Palacios, MF [1 ]
Scolnik, MP [1 ]
机构
[1] Acad Nacl Med, IIHEMA, Clin Hematol, Inst Invest Hematol Mariano R Castex, RA-1425 Buenos Aires, DF, Argentina
关键词
MRD in hairy cell leukemia; pow cytometry; immunohistochemistry;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hairy cell leukemia patients in complete remission may have minimal residual disease (MRD), We performed flow cytometry (FCM) and immunohistochemistry (IHC) to detect MRD in 15 patients. FCM and IHC detected MRD+ in 64% and 46 % of the patients, respectively. MRD+ did not predict relapse.
引用
收藏
页码:1227 / 1229
页数:3
相关论文
共 50 条
  • [41] Immunophenotypic expression and immunomodulation in minimal residual disease analysis of pediatric B acute lymphoblastic leukemia by high sensitive flow cytometry
    Arumugam, Jhansi Rani
    Bommannan, Karthik
    Radhakrishnan, Venkatraman
    Sagar, Tenali Gnana
    Sundersingh, Shirley
    LEUKEMIA & LYMPHOMA, 2022, 63 (03) : 644 - 652
  • [42] Evaluation of Measurable Residual Disease Assessment Dynamics in Hairy Cell Leukemia Clinical Trials from 1980 to 2020
    Montes, Oscar Borja
    Jawadi, Altamash
    Varatharaj, Sushrruti
    Herring, Hannah E.
    Gil, Tomas Escobar
    Epperla, Narendranath
    Andritsos, Leslie A.
    BLOOD, 2024, 144 : 7787 - 7788
  • [43] Measurable residual disease in hairy cell leukemia: Technical considerations and clinical significance
    Robak, Tadeusz
    Robak, Pawel
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [44] Minimal residual disease may predict bone marrow relapse in patients with hairy cell leukemia treated with 2-chlorodeoxyadenosine
    Wheaton, S
    Tallman, MS
    Hakimian, D
    Peterson, L
    BLOOD, 1996, 87 (04) : 1556 - 1560
  • [45] MONOCLONAL ANTIBODY-B-LY7 - A SENSITIVE MARKER FOR DETECTION OF MINIMAL RESIDUAL DISEASE IN HAIRY-CELL LEUKEMIA
    THALER, J
    DIETZE, O
    FABER, V
    GREIL, R
    GASTL, G
    DENZ, H
    HO, AD
    HUBER, H
    LEUKEMIA, 1990, 4 (03) : 170 - 176
  • [46] IMMUNOCYTOCHEMICAL DETECTION OF MINIMAL RESIDUAL DISEASE IN PATIENTS WITH HAIRY-CELL LEUKEMIA IN REMISSION AFTER 2-CHLORODEOXYADENOSINE TREATMENT
    CORDONE, I
    ANNINO, L
    FERRARI, A
    PESCARMONA, E
    PACCHIAROTTI, A
    GIUBILEI, E
    TESTA, MG
    BARONI, CD
    MANDELLI, F
    BLOOD, 1993, 82 (10) : A562 - A562
  • [47] Very long-term eradication of minimal residual disease in patients with hairy cell leukemia after a single course of cladribine
    Sigal, Darren S.
    Sharpe, Robert
    Burian, Carol
    Saven, Alan
    BLOOD, 2010, 115 (10) : 1893 - 1896
  • [48] PROGNOSTIC SIGNIFICANCE OF MINIMAL RESIDUAL DISEASE ASSESSMENT IN ACUTE MYELOID LEUKEMIA
    Ravandi-Kashani, Farhad
    LEUKEMIA RESEARCH, 2016, 49 : S8 - S8
  • [49] MOLECULAR ASSESSMENT OF MINIMAL RESIDUAL DISEASE IN ACUTE LYMPHOBLASTIC-LEUKEMIA
    SHIACH, CR
    EVANS, PAS
    SHORT, MA
    BAILEY, CC
    LEWIS, IJ
    KINSEY, SE
    BRITISH JOURNAL OF HAEMATOLOGY, 1993, 84 : 19 - 19
  • [50] Use of minimal residual disease assessment in the treatment of chronic lymphocytic leukemia
    Owen, Carolyn
    Christofides, Anna
    Johnson, Nathalie
    Lawrence, Tatiana
    MacDonald, David
    Ward, Carol
    LEUKEMIA & LYMPHOMA, 2017, 58 (12) : 2777 - 2785