Reversible Cerebral Vasoconstriction Syndromes and Primary Angiitis of the Central Nervous System: Clinical, Imaging, and Angiographic Comparison

被引：134

作者：

Singhal, Aneesh B. ^{[1
,2
]}

Topcuoglu, Mehmet A. ^{[1
,2
,3
]}

Fok, Joshua W. ^{[4
]}

Kursun, Oguzhan ^{[5
]}

Nogueira, Raul G. ^{[6
,7
]}

Frosch, Matthew P. ^{[1
,2
]}

Caviness, Verne S., Jr. ^{[1
,2
]}

机构：

[1] Massachusetts Gen Hosp, Boston, MA 02114 USA

[2] Harvard Univ, Sch Med, Boston, MA USA

[3] Hacettepe Univ Hosp, Dept Neurol, Ankara, Turkey

[4] Yan Chai Hosp, Dept Med, Hong Kong, Hong Kong, Peoples R China

[5] Ankara Numune Training & Res Hosp, Neurol Clin, Ankara, Turkey

[6] Grady Mem Hosp, Atlanta, GA USA

[7] Emory Univ, Sch Med, Atlanta, GA USA

来源：

ANNALS OF NEUROLOGY | 2016年 / 79卷 / 06期

关键词：

POSTERIOR LEUKOENCEPHALOPATHY; THUNDERCLAP HEADACHE; POSTPARTUM ANGIOPATHY; HYPERINTENSE VESSELS; VASCULITIS; CNS; HEMORRHAGE; DIAGNOSIS; STROKES; COHORT;

D O I：

10.1002/ana.24652

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Reversible cerebral vasoconstriction syndromes (RCVS) and primary angiitis of the central nervous system (PACNS) are invariably considered in the differential diagnosis of new cerebral arteriopathies. However, prompt and accurate diagnosis remains challenging. Here we compared the features of 159 RCVS to 47 PACNS patients and developed criteria for prompt bedside diagnosis. Recurrent thunderclap headache (TCH), and single TCH combined with either normal neuroimaging, border zone infarcts, or vasogenic edema, have 100% positive predictive value for diagnosing RCVS or RCVS-spectrum disorders. In patients without TCH and positive angiography, neuroimaging can discriminate RCVS (no lesion) from PACNS (deep/brainstem infarcts).

引用

页码：882 / 894

页数：13

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