Antibacterial activity of a stearic acid derivative from Stemodia foliosa

被引：24
|
作者：
da Silva, LLD
Nascimento, M
Silva, DHS
Furlan, M
Bolzani, VD
机构：
[1] Univ Estadual Paulista, Inst Quim, NuBBE, UNESP, BR-14801970 Araraquara, SP, Brazil
[2] Univ Fed Pernambuco, Dept Antibiot, Ctr Ciencias Biol, Recife, PE, Brazil
来源：
PLANTA MEDICA | 2002年 / 68卷 / 12期
关键词：
D O I：
10.1055/s-2002-36346
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
From the hexane-soluble fraction of an ethanol extract from leaves and stems of Stemodia foliosa (Scrophulariaceae), the new stearic acid 4-[(n-pentoxy)phenethyl] ester (1) was isolated. This compound exhibited antibacterial properties at 10 mug/mL concentration by using disc diffusion method against Gram-positive bacteria Bacillus cereus and Bacillus subtilis and fast-acid bacterium Mycobacterium fortuitum. The structure of the new compound was elucidated by spectroscopic methods and by chemical conversion.
引用
收藏
页码：1137 / 1139
页数：3
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