Perspectives on systems biology

被引:60
|
作者
Kitano, H
机构
[1] Sony Comp Sci Labs Inc, Tokyo 1410022, Japan
[2] Japan Sci & Technol Corp, ERATO, Kitano Symbiot Syst Project, Tokyo 1500001, Japan
[3] CALTECH, Pasadena, CA 91125 USA
关键词
system biology; simulation; gene network;
D O I
10.1007/BF03037529
中图分类号
TP3 [计算技术、计算机技术];
学科分类号
0812 ;
摘要
Systems biology is a new field in biology that aims at system-level understanding of biological systems, such as cells and organisms. Molecular biology has already made remarkable contribution to our understanding of biological systems, and its current focus is on the identification of genes and the functions of their products; that is, on the components of systems. There is no doubt that molecular biology will progress even faster and finally identify all the components of biological systems. As such a moment approaches, major importance need to be placed on the establishment of methodologies and techniques that enable us to understand biological systems as systems. This paper overviews the field of systems biology.
引用
收藏
页码:199 / 216
页数:18
相关论文
共 50 条
  • [41] Systems Biology Reveals Biology of Systems
    Bertolaso, Marta
    Giuliani, Alessandro
    De Gara, Laura
    COMPLEXITY, 2011, 16 (06) : 10 - 16
  • [42] Perspectives of a Systems Biology of the Brain: The Big Data Conundrum Understanding Psychiatric Diseases
    Mewes, H. W.
    PHARMACOPSYCHIATRY, 2013, 46 : S2 - S9
  • [43] Metabolic systems biology and multi-omics of cyanobacteria: Perspectives and future directions
    Pathania, Ruchi
    Srivastava, Amit
    Srivastava, Shireesh
    Shukla, Pratyoosh
    BIORESOURCE TECHNOLOGY, 2022, 343
  • [44] Perspectives of a Systems Biology of the Synapse: How to Transform an Indefinite Data Space into a Model?
    Mewes, H. W.
    Wachinger, B.
    Stuempflen, V.
    PHARMACOPSYCHIATRY, 2010, 43 : S2 - S8
  • [45] Systems biology: perspectives on multiscale modeling in research on endocrine-related cancers
    Clarke, Robert
    Tyson, John J.
    Tan, Ming
    Baumann, William T.
    Jin, Lu
    Xuan, Jianhua
    Wang, Yue
    ENDOCRINE-RELATED CANCER, 2019, 26 (06) : R345 - R368
  • [46] Systems biology of resilience and optimal health:integrating Chinese and Western medicine perspectives
    Herman van Wietmarschen
    Yan Schroёn
    Victor Kallen
    Marvin Steijaert
    Albert A.de Graaf
    Ben van Ommen
    Jan van der Greef
    WorldJournalofTraditionalChineseMedicine, 2017, 3 (01) : 38 - 49
  • [47] Systems Biology of Gastric Cancer: Perspectives on the Omics-Based Diagnosis and Treatment
    Shi, Xiao-Jing
    Wei, Yongjun
    Ji, Boyang
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2020, 7
  • [48] Future perspectives of personalized medicine in traditional Chinese medicine: A systems biology approach
    Zhang, Aihua
    Sun, Hui
    Wang, Ping
    Han, Ying
    Wang, Xijun
    COMPLEMENTARY THERAPIES IN MEDICINE, 2012, 20 (1-2) : 93 - 99
  • [49] Teachers' and educators' perspectives on systems thinking and its implementation in Dutch biology education
    Gilissen, Melde G. R.
    Knippels, Marie-Christine P. J.
    Verhoeff, Roald P.
    van Joolingen, Wouter R.
    JOURNAL OF BIOLOGICAL EDUCATION, 2020, 54 (05) : 485 - 496
  • [50] Perspectives in inorganic structural biology
    Banci, L
    JOURNAL OF INORGANIC BIOCHEMISTRY, 1999, 74 (1-4) : 3 - 3