An insertion/deletion in the porcine FGFR2 gene

被引：3

作者：

Aldenhoven, J.

Spoetter, A.

Distl, O.

机构：

[1] Univ Vet Med, Inst Anim Breeding & Genet, D-30559 Hannover, Germany

[2] Univ Sydney, Fac Vet Sci, Ctr Adv Technol Anim Genet & Reprod Reprogen, Sydney, NSW 2006, Australia

来源：

JOURNAL OF ANIMAL BREEDING AND GENETICS | 2007年 / 124卷 / 01期

关键词：

fibroblast growth factor; gene mapping; pig;

D O I：

10.1111/j.1439-0388.2007.00629.x

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

The 7000-rad INRA-University of Minnesota porcine Radiation Hybrid panel was used to localize the FGFR2 gene on Sus scrofa chromosome 14 (SSC14). An insertion/deletion mutation of approximately 240 bp was detected in the porcine FGFR2 gene. This mutation consists of a repeat motif of 48 bp. In a short and long variant of this polymorphism, the motif was repeated either six or 11 times. The mutation was shown to follow a Mendelian mode of inheritance in 10 families including 48 pigs of Large White x Duroc origin.

引用

页码：39 / 41

页数：3

共 50 条

[41] FGFR2/3 in urothelial carcinoma
Rose, Michael
Gaisa, Nadine T.
PATHOLOGIE, 2024, 45 (06): : 409 - 411
[42] FGFR2 MUTATIONS IN PFEIFFER SYNDROME
LAJEUNIE, E
MA, HW
BONAVENTURE, J
MUNNICH, A
LEMERRER, M
RENIER, D
NATURE GENETICS, 1995, 9 (02) : 108 - 108
[43] Polyclonal secondary FGFR2 mutations drive acquired resistance to FGFR inhibition in FGFR2 fusion-positive cholangiocarcinoma patients
Goyal, Lipika
Saha, Supriya K.
Liu, Leah Y.
Siravegna, Giulia
Leshchiner, Ignaty
Ahronian, Leanne G.
Lennerz, Jochen K.
Phuong Vu
Mussolin, Benedetta
Reyes, Stephanie
Furet, Pascal
Iafrate, A. John
Getz, Gad
Porta, Diana G.
Tiedt, Ralph
Bardelli, Alberto
Juric, Dejan
Corcoran, Ryan B.
Bardeesy, Nabeel
Zhu, Andrew X.
CANCER RESEARCH, 2017, 77
[44] Inactivation of fgfr1 and fgfr2 in Postnatal Astrocytes
Rubin, L. B.
Smith, K.
INTEGRATIVE AND COMPARATIVE BIOLOGY, 2017, 57 : E392 - E392
[45] Discovery and Therapeutic Potential of FGFR2 Gene Amplification in Diffuse Gastric Cancer
Lau, Wen Min
Zang, Zhi Jiang
Teng, Eileen
Das, Kakoli
Yong, Wei-Peng
Teh, Ming
Tan, Jin Wei
Chia, Li Ming Tania
Tay, Amy
Shabbir, Asim
Kono, Koji
Chan, Shing Leng
Tan, Patrick
So, Jimmy B.
GASTROENTEROLOGY, 2014, 146 (05) : S151 - S151
[46] RFLPs at the porcine growth hormone receptor (GHR) gene: evidence of an insertion/deletion
Nielsen, VH
Larsen, NJ
Thomsen, B
ANIMAL GENETICS, 1998, 29 (05) : 400 - 401
[47] Quantitative assessment of the effect of FGFR2 gene polymorphism on the risk of breast cancer
Jia, Chenyou
Cai, Yu
Ma, Yushui
Fu, Da
BREAST CANCER RESEARCH AND TREATMENT, 2010, 124 (02) : 521 - 528
[48] A novel FGFR2 gene mutation in Crouzon syndrome associated with apparent nonpenetrance
Everett, ET
Britto, DA
Ward, RE
Hartsfield, JK
CLEFT PALATE-CRANIOFACIAL JOURNAL, 1999, 36 (06): : 533 - 541
[49] FGFR2 is a breast cancer susceptibility gene in Jewish and Arab Israeli populations
Raskin, Leon
Pinchev, Mila
Arad, Chana
Lejbkowicz, Flavio
Tamir, Ada
Rennert, Hedy S.
Rennert, Gad
Gruber, Stephen B.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2008, 17 (05) : 1060 - 1065
[50] Methylation of the FGFR2 gene is associated with high birth weight centile in humans
Haworth, Kim E.
Farrell, William E.
Emes, Richard D.
Ismail, Khaled M. K.
Carroll, William D.
Hubball, Emma
Rooney, Angela
Yates, Alexandra M.
Mein, Charles
Fryer, Anthony A.
EPIGENOMICS, 2014, 6 (05) : 477 - 491

← 1 2 3 4 5 →