Increasing antibiotic resistance in microorganisms and new emerging pathogens have become a major problem in our society. Rising to satisfy this urgent medical need is a recent confluence of powerful new drug discovery technologies: combinatorial chemistry; sequence and functional genomic analysis; and novel methods of high-throughput screening. The combination of these technologies will bring to bear untapped power in the search for new antimicrobials. (C) Current Biology Ltd ISSN 0958-1669.
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Bunin, Barry
Weatherall, Charlie
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Weatherall, Charlie
Gregory, Kellan
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Gregory, Kellan
Ernst, Sylvia
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Ernst, Sylvia
Ekins, Sean
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Ekins, Sean
Kallel, E. Adam
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Kallel, E. Adam
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY,
2014,
248
机构:
Karolinska Inst, Ctr Mol Med, Dept Med Solna, Expt Cardiovasc Res Unit, S-17177 Stockholm, SwedenBaylor Coll Med, Integrat Biol, Houston, TX 77030 USA