DISTINCT EXPRESSION OF IL-36α, β, γ AND THEIR ANTAGONISTS IL-36RA AND IL-38 IN PSORIASIS, RHEUMATOID ARTHRITIS (RA) AND CROHN'S DISEASE (CD)

被引:0
|
作者
Boutet, M. A. [1 ,2 ]
Bart, G. [1 ,2 ,3 ]
Gahier, M. [1 ,2 ,3 ]
Amiaud, J. [1 ,2 ]
Brulin, B. [1 ,2 ]
Charrier, C. [1 ,2 ]
Morel, F. [4 ]
Lecron, J-C [4 ,5 ]
Rolli-Derkinderen, M. [6 ]
Boureille, A. [6 ,7 ]
Vigne, S. [8 ,9 ]
Gabay, C. [8 ,9 ]
Palmer, G. [8 ,9 ]
Le Goff, B. [1 ,2 ,3 ]
Blanchard, F. [1 ,2 ]
机构
[1] INSERM, UMR 957, 1 Rue Gaston Veil, F-44035 Nantes, France
[2] Univ Nantes, Nantes Atlantique Univ, Lab Physiopathol La Resorpt Osseuse, Fac Med, 1 Rue Gaston Veil, F-44035 Nantes, France
[3] Nantes Univ Hosp, Rheumatol Unit, 1 Pl Alexis Ricordeau, F-44093 Nantes, France
[4] Univ Poitiers, EA 4331, 1 Rue Georges Bonnet, F-86073 Poitiers, France
[5] Univ Poitiers Hosp, Serv Immunol Inflammat, Rue Jacques Coeur, F-86021 Poitiers, France
[6] INSERM, UMR913, 1 Rue Gaston Veil, F-44035 Nantes, France
[7] Nantes Univ Hosp, Serv Hepatogastroenterol, 1 Pl Alexis Ricordeau, F-44093 Nantes, France
[8] Univ Hosp Geneva, Dept Internal Med, Div Rheumatol, Ave Beau Sejour, CH-1211 Geneva 4, Switzerland
[9] Univ Geneva, Dept Pathol Immunol, Sch Med, Ave Beau Sejour, CH-1211 Geneva 4, Switzerland
关键词
D O I
10.1136/annrheumdis-2016-209124.144
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A7.13
引用
收藏
页码:A60 / A61
页数:2
相关论文
共 50 条
  • [41] Digenic inheritance of IL-36RA and SEC61A1 mutations underlies generalized pustular psoriasis with hypogammaglobulinemia
    Almutairi, Abduarahman
    Amin, Maha M.
    Rashwan, Mohamed A. M.
    Elnagdy, Marwa H.
    Rizk, Ragheed
    Bahgat, Sara A.
    Platt, Craig D.
    Sobh, Ali
    CLINICAL IMMUNOLOGY, 2022, 235
  • [42] Plasma IL-10, IL-17, IL-35, IL-36 levels and their relationship with disease severity in psoriasis
    Acikgoz, B.
    Ozbagcivan, O.
    Aktan, S.
    Akhisaroglu, S. Tanriverdi
    Said, H. M.
    FEBS OPEN BIO, 2021, 11 : 452 - 452
  • [43] Co-expression of interleukin (IL)-17RA and IL-36γ in the hypothalamic paraventricular nucleus of the stress-induced hypertension rats
    Zhang, Hong
    Ding, Tingyu
    Zhang, Wenying
    Wu, Changhao
    Chen, Yupin
    Jiang, Jinjin
    Sun, Jihu
    Wu, Qin
    EUROPEAN JOURNAL OF INFLAMMATION, 2024, 22
  • [44] Evaluating Serum Levels of IL-33, IL-36, IL-37 and Gene Expression of IL-37 in Patients with Psoriasis Vulgaris
    Sehat, Mojtaba
    Talaei, Rezvan
    Dadgostar, Ehsan
    Nikoueinejad, Hassan
    Akbari, Hossein
    IRANIAN JOURNAL OF ALLERGY ASTHMA AND IMMUNOLOGY, 2018, 17 (02) : 179 - 187
  • [45] Role of IL-36RA on human chondrocyte homeostasis in osteoarthritis and post-traumatic osteoarthritis models
    Mishra, Pranav Kumar
    Meka, Sai Rama Krishna
    Kluppel, Michael
    Hakimiyan, Arnavaz
    Chubinskaya, Susan
    Wimmer, Markus
    Spagnoli, Anna
    JOURNAL OF BONE AND MINERAL RESEARCH, 2024, 39 : 125 - 125
  • [46] Opposing Effects of IL-1Ra and IL-36Ra on Innate Immune Response to Pseudomonas aeruginosa Infection in C57BL/6 Mouse Corneas
    Gao, Nan
    Me, Rao
    Dai, Chenyang
    Seyoum, Berhane
    Yu, Fu-Shin X.
    JOURNAL OF IMMUNOLOGY, 2018, 201 (02): : 688 - 699
  • [47] Establishment of in vitro model of IL-36Ra dysfunction in a human keratinocyte cell line by IL36RN knockout using CRISPR/Cas9 system
    Yamaguchi, A.
    Takahashi, T.
    Satoh, T.
    Fujimoto, N.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2023, 143 (05) : S151 - S151
  • [48] IL-1家族新成员IL-36、IL-37和IL-38在炎症性疾病中的作用
    徐可叶
    蒋雯雯
    彭笑
    李燕
    李明才
    现代免疫学, 2018, 38 (04) : 337 - 341
  • [49] IL-36 and IL-17A Cooperatively Induce a Psoriasis-Like Gene Expression Response in Human Keratinocytes
    Miura, Shunsuke
    Garcet, Sandra
    Salud-Gnilo, Charissa
    Gonzalez, Juana
    Li, Xuan
    Murai-Yamamura, Mika
    Yamamura, Kazuhiko
    Rambhia, Darshna
    Kunjravia, Norma
    Guttman-Yassky, Emma
    Krueger, James G.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2021, 141 (08) : 2086 - +
  • [50] 银屑病患者CC趋化因子配体20、IL-36及其受体拮抗剂IL-36Ra水平与脂代谢相关性分析
    周慧丽
    贵州医药, 2019, 43 (02) : 193 - 196