DISTINCT EXPRESSION OF IL-36α, β, γ AND THEIR ANTAGONISTS IL-36RA AND IL-38 IN PSORIASIS, RHEUMATOID ARTHRITIS (RA) AND CROHN'S DISEASE (CD)

被引：0
|
作者：
Boutet, M. A. [1 ,2 ]
Bart, G. [1 ,2 ,3 ]
Gahier, M. [1 ,2 ,3 ]
Amiaud, J. [1 ,2 ]
Brulin, B. [1 ,2 ]
Charrier, C. [1 ,2 ]
Morel, F. [4 ]
Lecron, J-C [4 ,5 ]
Rolli-Derkinderen, M. [6 ]
Boureille, A. [6 ,7 ]
Vigne, S. [8 ,9 ]
Gabay, C. [8 ,9 ]
Palmer, G. [8 ,9 ]
Le Goff, B. [1 ,2 ,3 ]
Blanchard, F. [1 ,2 ]
机构：
[1] INSERM, UMR 957, 1 Rue Gaston Veil, F-44035 Nantes, France
[2] Univ Nantes, Nantes Atlantique Univ, Lab Physiopathol La Resorpt Osseuse, Fac Med, 1 Rue Gaston Veil, F-44035 Nantes, France
[3] Nantes Univ Hosp, Rheumatol Unit, 1 Pl Alexis Ricordeau, F-44093 Nantes, France
[4] Univ Poitiers, EA 4331, 1 Rue Georges Bonnet, F-86073 Poitiers, France
[5] Univ Poitiers Hosp, Serv Immunol Inflammat, Rue Jacques Coeur, F-86021 Poitiers, France
[6] INSERM, UMR913, 1 Rue Gaston Veil, F-44035 Nantes, France
[7] Nantes Univ Hosp, Serv Hepatogastroenterol, 1 Pl Alexis Ricordeau, F-44093 Nantes, France
[8] Univ Hosp Geneva, Dept Internal Med, Div Rheumatol, Ave Beau Sejour, CH-1211 Geneva 4, Switzerland
[9] Univ Geneva, Dept Pathol Immunol, Sch Med, Ave Beau Sejour, CH-1211 Geneva 4, Switzerland
来源：
ANNALS OF THE RHEUMATIC DISEASES | 2016年 / 75卷
关键词：
D O I：
10.1136/annrheumdis-2016-209124.144
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A7.13
引用
收藏
页码：A60 / A61
页数：2
相关论文
共 50 条
  • [1] Distinct expression of interleukin (IL)-36α, β and γ, their antagonist IL-36Ra and IL-38 in psoriasis, rheumatoid arthritis and Crohn's disease
    Boutet, M. -A.
    Bart, G.
    Penhoat, M.
    Amiaud, J.
    Brulin, B.
    Charrier, C.
    Morel, F.
    Lecron, J. -C.
    Rolli-Derkinderen, M.
    Bourreille, A.
    Vigne, S.
    Gabay, C.
    Palmer, G.
    Le Goff, B.
    Blanchard, F.
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2016, 184 (02): : 159 - 173
  • [2] Distinct Expression of IL-36(I)over-cap, β, (I)over-cap3 and Their Antagonists IL-36Ra and IL-38 in Psoriasis, Rheumatoid Arthritis and Crohn's Disease
    Boutet, Marie-Astrid
    Bart, Geraldine
    Amiaud, Jerome
    Brulin, Benedicte
    Charrier, Celine
    Morel, Franck
    Lecron, Jean-Claude
    Rolli-Derkinderen, Malvyne
    Boureille, Arnaud
    Gabay, Cem
    Palmer, Gaby
    Le Goff, Benoit
    Blanchard, Frederic
    ARTHRITIS & RHEUMATOLOGY, 2015, 67
  • [3] Profile of IL-36 cytokines (IL-36α, IL-36β, IL-36γ and IL-36Ra) in patients with primary immune thrombocytopenia
    Wang, Shuang
    Liu, Yang
    Nie, Mu
    Li, Qianpeng
    Liu, Yu
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2020, 82
  • [4] Role of IL-36RA mutations in Crohn's disease
    Hecker, J.
    Saurenbach, J.
    Letizia, M.
    Loescher, B. S.
    Franke, A.
    Kuehl, A. A.
    Atreya, R.
    Koop, K.
    Neufert, C.
    Trajanoski, Z.
    Schuetz, A.
    Siegmund, B.
    Weidinger, C.
    JOURNAL OF CROHNS & COLITIS, 2023, 17 : I183 - I183
  • [5] Interleukin-36 (IL-36) Ligands Require Processing for Full Agonist (IL-36α, IL-36β, and IL-36γ) or Antagonist (IL-36Ra) Activity
    Towne, Jennifer E.
    Renshaw, Blair R.
    Douangpanya, Jason
    Lipsky, Brian P.
    Shen, Min
    Gabel, Christopher A.
    Sims, John E.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (49) : 42594 - 42602
  • [6] Altered serum levels of IL-36 cytokines (IL-36α, IL-36β, IL-36γ, and IL-36Ra) and their potential roles in Guillain-Barre syndrome
    Zhao, Zhikang
    Zhang, Rui
    Gao, Xinxin
    Li, Hui
    Liu, Hongbo
    MEDICINE, 2020, 99 (52)
  • [7] IL-36α/IL-36RA/IL-38 signaling mediates inflammation and barrier disruption in human corneal epithelial cells under hyperosmotic stress
    Li, Jin-Miao
    Lu, Rong
    Zhang, Yun
    Lin, Jing
    Hua, Xia
    Pflugfelder, Stephen C.
    Li, De-Quan
    OCULAR SURFACE, 2021, 22 : 163 - 171
  • [8] Distinct Regulatory Effects of IL-36Ra on IL-1β- and IL-36α-Mediated Inflammatory Responses in Articular Chondrocytes
    Meka, Sai Rama Krishna
    Mishra, Pranav Kumar
    Kluppel, Michael
    Torquati, Alfonso
    Spagnoli, Anna
    JOURNAL OF BONE AND MINERAL RESEARCH, 2024, 39 : 124 - 125
  • [9] IL-36 signaling in Crohn's disease - characterization of a patient with an IL36RA mutation
    Hecker, J.
    Letizia, M.
    Loescher, B. S.
    Franke, A.
    Weidinger, C.
    Siegmund, B.
    JOURNAL OF CROHNS & COLITIS, 2022, 16 : I167 - I167
  • [10] Interleukin (IL)-8 and IL-36γ but not IL-36Ra are related to acrosyringia in pustule formation associated with palmoplantar pustulosis
    Xiaoling, Y.
    Chao, W.
    Wenming, W.
    Feng, L.
    Hongzhong, J.
    CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2019, 44 (01) : 52 - 57
12345