Radiation-Induced Bystander Effect Research: Literature Review

被引:0
|
作者
Paluch-Ferszt, M. [1 ]
Kazmierczak, U. [1 ]
Szeflinski, Z. [1 ]
机构
[1] Univ Warsaw, Heavy Ion Lab, L Pasteura 5A, PL-02093 Warsaw, Poland
关键词
JUNCTIONAL INTERCELLULAR COMMUNICATION; IRRADIATION-INDUCED ANGIOGENESIS; TUMOR-NECROSIS-FACTOR; ENDOTHELIAL-CELLS; HUMAN FIBROBLASTS; IONIZING-RADIATION; GLIOMA-CELLS; GENOMIC INSTABILITY; SIGNALING PATHWAYS; LET RADIATION;
D O I
10.12693/APhysPolA.139.266
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
The aim of the present study is to review literature on radiation-induced bystander effect research. The radiation-induced bystander effect concerns a plethora of biological phenomena occurring in non-irradiated cells as a result of signal transmission from irradiated cells. This paper discusses many radiation-induced bystander effect in vitro experiments, e.g., for numerous types of cell lines or tumor cells. The influence of nanomaterials on the radiation-induced bystander effect is analyzed. Moreover, the relationship between the radiation-induced bystander effect and the radiation-induced senescence, inflammatory pathways and endothelial cells is discussed. The authors have tried to explore as many mechanisms accompanying the radiation-induced bystander effect as possible. The in-depth mechanism research on cell proliferation influenced by the bystander effect of radiation will be useful to understand the biological effects of radiation.
引用
收藏
页码:266 / 272
页数:7
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