Therapeutic potential of lefamulin in the treatment of community-acquired pneumonia

被引:9
|
作者
Perry, Whitney [1 ]
Golan, Yoav [1 ]
机构
[1] Tufts Med Ctr, Div Geog Med & Infect Dis, Boston, MA 02111 USA
关键词
community acquired; lefamulin; pneumonia; PLEUROMUTILIN ANTIBIOTIC BC-3781; ACUTE BACTERIAL SKIN; ANTIMICROBIAL ACTIVITY; DERIVATIVES; RESISTANCE; COMPOUND;
D O I
10.2217/fmb-2019-0027
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Despite the increasing availability of antibiotics with activity against pathogens that cause community-acquired pneumonia (CAP), CAP remains a major cause of morbidity, hospital admissions and readmissions, and mortality. Lefamulin is a novel pleuromutilin antibiotic with potent in vitro activity against both typical and atypical CAP pathogens. In this review of the medical literature, we summarize the available information, including mounting clinical evidence, about lefamulin and its potential value in CAP.
引用
收藏
页码:927 / 939
页数:13
相关论文
共 50 条
  • [21] Myristoyl lysophosphatidylcholine is a biomarker and potential therapeutic target for community-acquired pneumonia
    Nan, Wengang
    Xiong, Fen
    Zheng, Hong
    Li, Chen
    Lou, Cong
    Lei, Xiong
    Wu, Huizhen
    Gao, Hongchang
    Li, Yuping
    REDOX BIOLOGY, 2022, 58
  • [22] Community-acquired pneumonia - Diagnostic and therapeutic approach
    Cunha, BA
    MEDICAL CLINICS OF NORTH AMERICA, 2001, 85 (01) : 43 - +
  • [23] Tigecycline in the Treatment of Community-Acquired Pneumonia
    Curcio, Daniel
    CLINICAL MEDICINE INSIGHTS-THERAPEUTICS, 2009, 1 : 1275 - 1289
  • [24] Glucocorticoid treatment in community-acquired pneumonia
    Confalonieri, Marco
    Meduri, G. Umberto
    LANCET, 2011, 377 (9782): : 1982 - 1984
  • [25] Empirical treatment of community-acquired pneumonia
    Ferrer, VF
    Gragera, BA
    Berga, AP
    REVISTA CLINICA ESPANOLA, 2004, 204 (02): : 103 - 105
  • [26] Antimicrobial treatment of community-acquired pneumonia
    Restrepo, MI
    Anzueto, A
    CLINICS IN CHEST MEDICINE, 2005, 26 (01) : 65 - +
  • [27] Treatment failure in community-acquired pneumonia
    Menendez, Rosario
    Torres, Antoni
    CHEST, 2007, 132 (04) : 1348 - 1355
  • [28] CEFOXITIN IN THE TREATMENT OF COMMUNITY-ACQUIRED PNEUMONIA
    SALZMAN, C
    POLLY, SM
    SIMON, GL
    CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, 1987, 41 (05): : 785 - 789
  • [29] Current treatment of community-acquired pneumonia
    Liapikou, Adamantia
    Torres, Antonio
    EXPERT OPINION ON PHARMACOTHERAPY, 2013, 14 (10) : 1319 - 1332
  • [30] Azithromycin in the treatment of community-acquired pneumonia
    Golec, K
    RzeszutkoGrabowska, M
    BukowskaNierojewska, D
    EXPANDING INDICATIONS FOR THE NEW MACROLIDES, AZALIDES, AND STREPTOGRAMINS, 1997, 21 : 626 - 628