Vincristine, an efficacious alternative for diffuse neonatal haemangiomatosis

被引：10
|
作者：
Perez-Valle, S. [1 ]
Peinador, M. [1 ]
Herraiz, P. [1 ]
Saenz, P. [1 ]
Montoliu, G. [1 ]
Vento, M. [1 ]
机构：
[1] Hosp Univ Materno Infantil La Fe, Serv Neonatol, E-46009 Valencia, Spain
来源：
ACTA PAEDIATRICA | 2010年 / 99卷 / 02期
关键词：
Corticosteroids; Diffuse neonatalhaemangiomatosis; Vincristine; THERAPY; INFANCY; CYCLOPHOSPHAMIDE; TUMOR;
D O I：
10.1111/j.1651-2227.2009.00466.x
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Diffuse neonatal haemangiomatosis (DNH) is an uncommon condition characterized by multiple cutaneous and visceral haemangiomas frequently causing severe complications. Corticosteroids constitute the first therapeutic line; however, when they fail, other alternatives are available, provided possible side effects are closely monitored during and after treatment. We present a case of life-threatening DNH, non-responsive to corticosteroids, successfully treated with Vincristine with minor side effects. We conclude that Vincristine is a valid alternative in corticosteroid-resistant DNH.
引用
收藏
页码：311 / 315
页数：6
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