Faecal microbiota transplantation for recurrent Clostridioides difficile infection: an Australian experience - effective, safe, yet room for improvement

被引：2
|
作者：
Chauhan, Ayushi [1 ]
Apostolov, Ross [1 ]
van Langenberg, Daniel [1 ,2 ]
Garg, Mayur [1 ,2 ,3 ,4 ]
机构：
[1] Eastern Hlth, Dept Gastroenterol, Melbourne, Vic, Australia
[2] Monash Univ, Eastern Hlth Clin Sch, Melbourne, Vic, Australia
[3] Royal Melbourne Hosp, Dept Gastroenterol & Hepatol, Melbourne, Vic, Australia
[4] Univ Melbourne, Dept Med, Melbourne, Vic, Australia
来源：
INTERNAL MEDICINE JOURNAL | 2021年 / 51卷 / 01期
关键词：
faecal microbiota transplantation; Clostridioides difficile; host− microbiota interaction; immune‐ mediated illness; ANA;
D O I：
10.1111/imj.15162
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Faecal microbiota transplantation (FMT) is reportedly effective and safe for the management of recurrent or refractory Clostridioides difficile infection (CDI), yet real-world data of outcomes of FMT in Australia are limited. In this series, FMT safely resulted in resolution of CDI in 19 patients with reduced healthcare utilisation after 25 FMT, but one patient was diagnosed with an anti-nuclear antibody-positive constitutional illness and Hashimoto thyroiditis following FMT. Further prospective evaluation of the utility of FMT earlier in CDI treatment algorithms to minimise cost and morbidity, and recipient follow up for immune-mediated conditions, is required.
引用
收藏
页码：106 / 110
页数：5
相关论文
共 50 条
  • [1] Faecal microbiota transplantation for recurrent Clostridioides difficile infection: experience with lyophilized oral capsules
    Reigadas, E.
    Bouza, E.
    Olmedo, M.
    Vazquez-Cuesta, S.
    Villar-Gomara, L.
    Alcala, L.
    Marin, M.
    Rodriguez-Fernandez, S.
    Valerio, M.
    Munoz, P.
    JOURNAL OF HOSPITAL INFECTION, 2020, 105 (02) : 319 - 324
  • [2] Faecal microbiota transplantation for Clostridioides difficile infection
    Waldbaum, Carlos
    Lopez, Fabiana
    Antelo, Pablo
    Sorda, Juan
    MEDICINA-BUENOS AIRES, 2020, 80 (06) : 633 - 639
  • [3] Faecal Microbiota Transplantation for Recurrent Clostridioides Difficile in Paediatric Renal Transplantation
    Eryilmaz, Cansu Ceren
    Arslan, Zainab
    Dixon, Garth
    Hatcher, James
    Jones, Kelsey
    Klein, Nigel
    Shingadia, Delane
    Stojanovic, Jelena
    Marks, Stephen D.
    PEDIATRIC NEPHROLOGY, 2024, 39 (01) : S393 - S393
  • [4] Faecal microbiota transplantation for treatment of recurrent or refractory Clostridioides difficile infection in Hong Kong
    Lui, Rashid N.
    Wong, Sunny H.
    Lau, Louis H. S.
    Chan, T. T.
    Cheung, Kitty C. Y.
    Li, Amy Y. L.
    Chin, M. L.
    Tang, Whitney W. Y.
    Ching, Jessica Y. L.
    Lam, Kelvin L. Y.
    Chan, Paul K. S.
    Wu, Justin C. Y.
    Sung, Joseph J. Y.
    Chan, Francis K. L.
    Ng, Siew C.
    HONG KONG MEDICAL JOURNAL, 2019, 25 (03) : 178 - 182
  • [5] Fecal Microbiota Transplantation Is Safe and Effective in Patients With Clostridioides difficile Infection and Cirrhosis
    Cheng, Yao-Wen
    Alhaffar, Dana
    Saha, Srishti
    Khanna, Sahil
    Bohm, Matthew
    Phelps, Emmalee
    Ghabril, Marwan
    Orman, Eric
    Sashidhar, Sagi
    Rogers, Nicholas
    Xu, Huiping
    Khoruts, Alexander
    Vaughn, Byron
    Kao, Dina
    Wong, Karen
    Cammarota, Giovanni
    Ianiro, Gianluca
    Dhere, Tanvi
    Kraft, Colleen S.
    Mehta, Nirja
    Woodworth, Michael H.
    Allegretti, Jessica R.
    Nativ, Lotem
    Marcus, Jenna
    El-Nachef, Najwa
    Fischer, Monika
    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2021, 19 (08) : 1627 - 1634
  • [6] Fecal microbiota transplantation for recurrent Clostridioides difficile infection
    Haber, Stacy L.
    Raney, Carrington R. K.
    Larson, Trent L.
    Lau, Jennifer Park
    AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2019, 76 (13) : 935 - 942
  • [7] Economic evaluation of Faecal microbiota transplantation compared to antibiotics for the treatment of recurrent Clostridioides difficile infection
    Abdali, Zainab, I
    Roberts, Tracy E.
    Barton, Pelham
    Hawkey, Peter M.
    ECLINICALMEDICINE, 2020, 24
  • [8] Faecal microbiota transplantation "safe, well tolerated" in recurrent C.difficile infection
    Reactions Weekly, 2023, 1967 (1) : 6 - 6
  • [9] The role of faecal microbiota transplantation: looking beyond Clostridioides difficile infection
    Goldenberg, Simon D.
    Merrick, Blair
    THERAPEUTIC ADVANCES IN INFECTIOUS DISEASE, 2021, 8
  • [10] Faecal microbiota transplantation for first and second episodes of Clostridioides difficile infection
    Krutova, Marcela
    Davis, Kerrie
    Guery, Benoit
    Barbut, Frederic
    LANCET GASTROENTEROLOGY & HEPATOLOGY, 2023, 8 (02): : 111 - 112
12345