GnRH blockers: a changing paradigm in the management of prostate cancer

被引：6
|
作者：
Drudge-Coates, Lawrence [1 ]
机构：
[1] Kings Coll Hosp London, Dept Urol, London SE5 9RS, England
来源：
INTERNATIONAL JOURNAL OF UROLOGICAL NURSING | 2009年 / 3卷 / 03期
关键词：
Androgen deprivation; Degarelix; Gonadotrophin-receptor blocker; Hormonal therapy; Prostate cancer; ANDROGEN DEPRIVATION THERAPY; OPEN-LABEL; HORMONE; CASTRATION; DEGARELIX; TESTOSTERONE; ANTAGONISTS; CARCINOMA; EFFICACY; SAFETY;
D O I：
10.1111/j.1749-771X.2009.01081.x
中图分类号：
R47 [护理学];
学科分类号：
1011 ;
摘要：
The development of GnRH blockers provides a new class of hormonal agent with a different, direct mode of action. Degarelix, a newly approved GnRH blocker, has displayed a fast, profound and sustained suppression of testosterone and prostate-specific antigen levels without subsequent tumour flare effects. This paper considers the current evidence for this new treatment approach and how this may impact on current urology nursing practice.
引用
收藏
页码：85 / 92
页数：8
相关论文
共 50 条
  • [21] GnRH superanalog implants for prostate cancer
    Spitz, IM
    Leiter, C
    Chertin, B
    Fridmans, A
    Koulikov, D
    Lindenberg, T
    Gelber, H
    Kuzma, P
    Farkas, A
    PROCEEDINGS OF THE 12TH INTERNATIONAL CONGRESS OF ENDOCRINOLOGY, 2004, : 389 - 395
  • [22] CHANGING THE PROSTATE CANCER DETECTION PARADIGM: CLINICAL APPLICATION OF MRI-BASED RISK STRATIFICATION IN MEN WITH SUSPECTED PROSTATE CANCER
    Tully, Karl
    Bahlburg, Henning
    Berg, Sebastian
    Hanske, Julian
    von Landenberg, Nicolas
    Noldus, Joachim
    Palisaar, Rein-Jueri
    Roghmann, Florian
    Brock, Marko
    JOURNAL OF UROLOGY, 2021, 206 : E76 - E76
  • [23] Are PSMA PET/CT scans changing the management of prostate cancer?
    Merrett, C.
    Silagy, B.
    Namdar, K.
    Shum, P. L.
    Vu, J.
    Manohar, P.
    BJU INTERNATIONAL, 2020, 125 : 106 - 106
  • [24] Changing Trends in Surgical Management of Prostate Cancer: The End of Overtreatment?
    Huland, Hartwig
    Graefen, Markus
    EUROPEAN UROLOGY, 2015, 68 (02) : 175 - 178
  • [25] Oligometastatic disease in prostate cancer, a continuously changing paradigm: patient selection and treatment strategy
    Fodor, Andrei
    Cozzarini, Cesare
    Fiorino, Claudio
    Di Muzio, Nadia Gisella
    TRANSLATIONAL CANCER RESEARCH, 2017, 6 : S112 - S116
  • [26] Changing the paradigm for pesticide resistance management
    Shaw, David R.
    Asmus, Amy B.
    Schroeder, Jill
    Ervin, David E.
    PEST MANAGEMENT SCIENCE, 2023, 79 (12) : 4726 - 4730
  • [27] Management of CVJ tuberculosis: the changing paradigm
    Mohindra, Sandeep
    Tripathi, Manjul
    Batish, Aman
    Mohindra, Satyawati
    Mahendru, Shaurya
    ACTA NEUROCHIRURGICA, 2020, 162 (11) : 2875 - 2886
  • [28] Changing paradigm in the management of childhood myopia
    Chen, Krystal S.
    Eong, Jonathan T. W. Au
    Eong, Kah-Guan Au
    EYE, 2024, 38 (06) : 1027 - 1028
  • [29] Management of CVJ tuberculosis: the changing paradigm
    Sandeep Mohindra
    Manjul Tripathi
    Aman Batish
    Satyawati Mohindra
    Shaurya Mahendru
    Acta Neurochirurgica, 2020, 162 : 2875 - 2886
  • [30] Changing paradigm in the management of childhood myopia
    Krystal S. Chen
    Jonathan T. W. Au Eong
    Kah-Guan Au Eong
    Eye, 2024, 38 : 1027 - 1028
12345