Optimized beam shaping assembly for a 2.1-MeV proton-accelerator-based neutron source for boron neutron capture therapy

被引:21
|
作者
Torres-Sanchez, Pablo [1 ]
Porras, Ignacio [1 ]
Ramos-Chernenko, Nataliya [1 ]
Arias de Saavedra, Fernando [1 ]
Praena, Javier [1 ]
机构
[1] Univ Granada, Fac Ciencias, Dept Fis Atom Mol & Nucl, Granada 18071, Spain
关键词
BNCT; FACILITY;
D O I
10.1038/s41598-021-87305-9
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Boron Neutron Capture Therapy (BNCT) is facing a new era where different projects based on accelerators instead of reactors are under development. The new facilities can be placed at hospitals and will increase the number of clinical trials. The therapeutic effect of BNCT can be improved if a optimized epithermal neutron spectrum is obtained, for which the beam shape assembly is a key ingredient. In this paper we propose an optimal beam shaping assembly suited for an affordable low energy accelerator. The beam obtained with the device proposed accomplishes all the IAEA recommendations for proton energies between 2.0 and 2.1 MeV. In addition, there is an overall improvement of the figures of merit with respect to BNCT facilities and previous proposals of new accelerator-based facilities.
引用
收藏
页数:12
相关论文
共 50 条
  • [21] Development of an Accelerator-Based Epithermal Neutron Source for Boron Neutron Capture Therapy
    Taskaev, S. Yu.
    PHYSICS OF PARTICLES AND NUCLEI, 2019, 50 (05) : 569 - 575
  • [22] Development of an Accelerator-Based Epithermal Neutron Source for Boron Neutron Capture Therapy
    S. Yu. Taskaev
    Physics of Particles and Nuclei, 2019, 50 : 569 - 575
  • [23] A shielding design for an accelerator-based neutron source for boron neutron capture therapy
    Hawk, AE
    Blue, TE
    Woollard, JE
    APPLIED RADIATION AND ISOTOPES, 2004, 61 (05) : 1027 - 1031
  • [24] An optimized neutron-beam shaping assembly for accelerator-based BNCT
    Burlon, AA
    Kreiner, AJ
    Vaida, AA
    Minsky, DM
    APPLIED RADIATION AND ISOTOPES, 2004, 61 (05) : 811 - 815
  • [25] Experimental and Simulated Characterization of a Beam Shaping Assembly for Accelerator-Based Boron Neutron Capture Therapy (AB-BNCT)
    Burlon, Alejandro A.
    Girola, Santiago
    Valda, Alejandro A.
    Minsky, Daniel M.
    Kreiner, Andres J.
    VIII LATIN AMERICAN SYMPOSIUM ON NUCLEAR PHYSICS AND APPLICATIONS, 2010, 1265 : 411 - 414
  • [26] Design for an accelerator-based orthogonal epithermal neutron beam for boron neutron capture therapy
    Allen, DA
    Beynon, TD
    Green, S
    MEDICAL PHYSICS, 1999, 26 (01) : 71 - 76
  • [27] Neutron beam design and dosimetric evaluation for accelerator-based Boron Neutron Capture Therapy
    Bortolussi, S.
    Postuma, I.
    Protti, N.
    Fatemi, S.
    Magni, C.
    Gonzalez, S.
    Altieri, S.
    RADIOTHERAPY AND ONCOLOGY, 2019, 133 : S1024 - S1024
  • [28] Current development status of accelerator-based neutron source for boron neutron capture therapy
    Kumada, Hiroaki
    Sakae, Takeji
    Sakurai, Hideyuki
    EPJ TECHNIQUES AND INSTRUMENTATION, 2023, 10 (01)
  • [29] Opportunities for Using an Accelerator-Based Epithermal Neutron Source for Boron Neutron Capture Therapy
    Taskaev S.Y.
    Kanygin V.V.
    Byvaltsev V.A.
    Zaboronok A.A.
    Volkova O.Y.
    Mechetina L.V.
    Taranin A.V.
    Kichigin A.I.
    Iarullina A.I.
    Eliseenko I.A.
    Nakai K.
    Sato E.
    Yamamoto T.
    Ishikawa E.
    Matsumura A.
    Biomedical Engineering, 2018, 52 (02) : 73 - 76
  • [30] First experiments on neutron detection on the accelerator-based source for boron neutron capture therapy
    A. S. Kuznetsov
    G. N. Malyshkin
    A. N. Makarov
    I. N. Sorokin
    Yu. S. Sulyaev
    S. Yu. Taskaev
    Technical Physics Letters, 2009, 35 : 346 - 348