Pharmacokinetic/pharmacodynamic (PK/PD) relationships for the angiogenesis inhibitor ABT-510 in preclinical efficacy models

被引:0
|
作者
Carr, R
Marsh, K
Schneider, A
Henkin, J
Wang, Y
Joseph, I
Khanna, C
Humerickhouse, R
机构
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
250
引用
收藏
页码:S79 / S79
页数:1
相关论文
共 50 条
  • [21] Enhancement of anti-PD-1 antitumor efficacy in syngeneic preclinical models by the angiogenesis inhibitor lucitanib
    Dusek, Rachel L.
    Robillard, Liliane
    Harding, Thomas C.
    Simmons, Andrew D.
    Minh Nguyen
    CANCER RESEARCH, 2019, 79 (13)
  • [22] A phase I study assessing the safety and pharmacokinetics of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 with gemcitabine and cisplatin in patients with solid tumors
    Gietema, J. A.
    Hoekstra, R.
    de Vos, F. Y. F. L.
    Uges, D. R. A.
    van der Gaast, A.
    Groen, H. J. M.
    Loos, W. J.
    Knight, R. A.
    Carr, R. A.
    Humerickhouse, R. A.
    Eskens, F. A. L. M.
    ANNALS OF ONCOLOGY, 2006, 17 (08) : 1320 - 1327
  • [23] Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer
    Carol, Hernan
    Boehm, Ingrid
    Reynolds, C. Patrick
    Kang, Min H.
    Maris, John M.
    Morton, Christopher L.
    Gorlick, Richard
    Kolb, E. Anders
    Keir, Stephen T.
    Wu, Jianrong
    Wozniak, Amy E.
    Yang, Yu
    Manfredi, Mark
    Ecsedy, Jeffrey
    Wang, Jianmin
    Neale, Geoffrey
    Houghton, Peter J.
    Smith, Malcolm A.
    Lock, Richard B.
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2011, 68 (05) : 1291 - 1304
  • [24] Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer
    Hernan Carol
    Ingrid Boehm
    C. Patrick Reynolds
    Min H. Kang
    John M. Maris
    Christopher L. Morton
    Richard Gorlick
    E. Anders Kolb
    Stephen T. Keir
    Jianrong Wu
    Amy E. Wozniak
    Yu Yang
    Mark Manfredi
    Jeffrey Ecsedy
    Jianmin Wang
    Geoffrey Neale
    Peter J. Houghton
    Malcolm A. Smith
    Richard B. Lock
    Cancer Chemotherapy and Pharmacology, 2011, 68 : 1291 - 1304
  • [25] A Microfluidic Perfusion Platform for In Vitro Analysis of Drug Pharmacokinetic-Pharmacodynamic (PK-PD) Relationships
    Yadir A. Guerrero
    Diti Desai
    Connor Sullivan
    Erick Kindt
    Mary E. Spilker
    Tristan S. Maurer
    Deepak E. Solomon
    Derek W. Bartlett
    The AAPS Journal, 22
  • [26] A Microfluidic Perfusion Platform for In Vitro Analysis of Drug Pharmacokinetic-Pharmacodynamic (PK-PD) Relationships
    Guerrero, Yadir A.
    Desai, Diti
    Sullivan, Connor
    Kindt, Erick
    Spilker, Mary E.
    Maurer, Tristan S.
    Solomon, Deepak E.
    Bartlett, Derek W.
    AAPS JOURNAL, 2020, 22 (02):
  • [27] POPULATION PHARMACOKINETIC (PK) AND PHARMACOKINETIC-PHARMACODYNAMIC (PK/PD) ASSESSMENT OF GDC-0334 (A TRPA1 INHIBITOR) IN HEALTHY SUBJECTS.
    Chan, H.
    Li, H.
    Liu, L.
    Ding, H.
    Ferl, G.
    Bauer, R.
    Gao, S.
    Joseph, V.
    Yang, X.
    Quartino, A.
    Putnam, W.
    Pan, L.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2020, 107 : S98 - S98
  • [28] Preclinical anti-tumor efficacy of ABT-510 (thrombospondin-1 mimetic peptide), a novel anti-angiogenic agent, in hematological malignancies.
    Cikojevic, A
    Wang, ES
    BLOOD, 2005, 106 (11) : 681A - 681A
  • [29] Pharmacokinetic (PK) / pharmacodynamic (PD) and efficacy relationship of selective inhibitors of nuclear export (KPT-SINE)
    Landesman, Yosef
    Senapedis, William
    Saint-Martin, Jean-Richard
    Kashyap, Trinayan
    Plamondon, Louis
    Sandanayaka, Vincent
    Shechter, Sharon
    Froim, Doriana
    McCauley, Dilara
    Kauffman, Michael
    Shacham, Sharon
    CANCER RESEARCH, 2012, 72
  • [30] DISTILLING KEY INFORMATION ON THE EFFICACY OF PULMONARY DRUG DELIVERY FROM PHARMACOKINETIC (PK) AND PHARMACODYNAMIC (PD) STUDIES
    Taylor, Glyn
    JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 2014, 27 (04) : A27 - A27