The Hedgehog Pathway and Pancreatic Cancer

被引：88
|
作者：
Hidalgo, Manuel [1 ]
Maitra, Anirban [2 ]
机构：
[1] Ctr Nacl Invest Oncol, Clin Res Program, Madrid, Spain
[2] Johns Hopkins Univ, Sch Med, Sol Goldman Pancreat Canc Res Ctr, Baltimore, MD USA
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2009年 / 361卷 / 21期
关键词：
INHIBITION;
D O I：
10.1056/NEJMcibr0905857
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：2094 / 2096
页数：3
相关论文
共 50 条
  • [11] Indian hedgehog signaling pathway:: Expression and regulation in pancreatic cancer
    Kayed, H
    Kleeff, J
    Keleg, S
    Guo, JC
    Ketterer, K
    Berberat, PO
    Giese, N
    Esposito, I
    Giese, T
    Büchler, MW
    Friess, H
    INTERNATIONAL JOURNAL OF CANCER, 2004, 110 (05) : 668 - 676
  • [12] The human hedgehog interacting protein gene is aberrantly methylated in pancreatic cancer and is a mediator of hedgehog pathway activity in pancreatic carcinogenesis
    Martin, ST
    Sato, N
    Hustinx, SR
    Dhara, S
    Abe, T
    Maitra, A
    Hruban, RH
    Goggins, M
    BRITISH JOURNAL OF SURGERY, 2005, 92 (10) : 1309 - 1310
  • [13] Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells
    Ji, Zhenyu
    Mei, Fang C.
    Xie, Jingwu
    Cheng, Xiaodong
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (19) : 14048 - 14055
  • [14] Gedunin inhibits pancreatic cancer by altering sonic hedgehog signaling pathway
    Subramani, Ramadevi
    Gonzalez, Elizabeth
    Nandy, Sushmita Bose
    Arumugam, Arunkumar
    Camacho, Fernando
    Medel, Joshua
    Alabi, Damilola
    Lakshmanaswamy, Rajkumar
    ONCOTARGET, 2017, 8 (07) : 10891 - 10904
  • [15] Hedgehog signaling pathway regulates human pancreatic cancer cell proliferation and metastasis
    Hao, Kun
    Tian, Xiao-Dong
    Qin, Chang-Fu
    Xie, Xue-Hai
    Yang, Yin-Mo
    ONCOLOGY REPORTS, 2013, 29 (03) : 1124 - 1132
  • [16] Hedgehog signalling in pancreatic cancer
    Hebrok, M
    GASTROENTEROLOGY YESTERDAY - TODAY - TOMORROW: A REVIEW AND PREVIEW, 2005, 144 : 234 - 243
  • [17] Dauricine suppresses the growth of pancreatic cancer in vivo by modulating the Hedgehog signaling pathway
    Zhang, Ying-Bo
    Fei, Hong-Xin
    Guo, Jia
    Zhang, Xiao-Jie
    Wu, Shu-Liang
    Zhong, Li-Li
    ONCOLOGY LETTERS, 2019, 18 (05) : 4403 - 4414
  • [18] Inhibition of the Hedgehog Pathway Targets the Tumor-Associated Stroma in Pancreatic Cancer
    Hwang, Rosa F.
    Moore, Todd T.
    Hattersley, Maureen Mertens
    Scarpitti, Meghan
    Yang, Bin
    Devereaux, Erik
    Ramachandran, Vijaya
    Arumugam, Thiruvengadam
    Ji, Baoan
    Logsdon, Craig D.
    Brown, Jeffrey L.
    Godin, Robert
    MOLECULAR CANCER RESEARCH, 2012, 10 (09) : 1147 - 1157
  • [19] Targeting the Hedgehog pathway in cancer
    Rubin, Lee L.
    de Sauvage, Frederic J.
    NATURE REVIEWS DRUG DISCOVERY, 2006, 5 (12) : 1026 - 1033
  • [20] The hedgehog pathway in breast cancer
    Sheikh Asim Ali
    Chinese Journal of Cancer Research, 2012, 24 (04) : 261 - 262
12345