Catalytic conjugate addition of allyl groups to styryl-activated enones

被引：89
|
作者：
Sieber, Joshua D.
Liu, Shubin
Morken, James P. [1 ]
机构：
[1] Boston Coll, Dept Chem, Merkert Chem Ctr, Chestnut Hill, MA 02467 USA
[2] Univ N Carolina, Informat Technol Serv, Div Res Comp, Chapel Hill, NC 27599 USA
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 08期
关键词：
D O I：
10.1021/ja067878w
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Conjugate addition of pinacolato(allyl)boron to benzylidenealkylidene ketones is remarkably facile when catalyzed by Ni(0) and Pd(0) complexes. Simple enones are inert to the reaction conditions, suggesting a significant activating effect by the auxiliary benzylidene unit. A comparison of different catalysts and substrates is provided, as is a mechanistic rationale, and an example of asymmetric catalysis.
引用
收藏
页码：2214 / +
页数：3
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