Case Report: Rapidly Progressive Interstitial Lung Disease in A Pregnant Patient With Anti-Melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis

被引:6
|
作者
Chen, Cuihong [1 ]
Chen, Yulan [1 ]
Huang, Qin [1 ]
Hu, Qiu [1 ]
Hong, Xiaoping [1 ]
机构
[1] Southern Univ Sci & Technol, Affiliated Hosp 1, Jinan Univ, Clin Med Coll 2,Dept Rheumatol & Immunol,Shenzhen, Shenzhen, Peoples R China
来源
FRONTIERS IN IMMUNOLOGY | 2021年 / 12卷
关键词
clinically amyopathic dermatomyositis; anti-melanoma differentiation-associated gene 5; rapidly progressive interstitial lung disease; pregnancy; treatment; CLINICALLY AMYOPATHIC DERMATOMYOSITIS; ANTI-MDA5; ANTIBODY; AUTOANTIBODIES; THERAPY; RISK;
D O I
10.3389/fimmu.2021.625495
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Dermatomyositis occurs extremely rarely during pregnancy. A number of studies in the published literature have documented how the outcome of pregnancy is poor for both mother and fetus. The present case study reports on a patient who was diagnosed with clinically amyopathic dermatomyositis complicated by interstitial lung disease during pregnancy, and was successfully treated with a combined immunosuppressant regimen. To the best of the authors' knowledge, this is the first case study detailing how a pregnant woman with clinically amyopathic dermatomyositis with positive anti-melanoma differentiation-associated gene 5 antibody achieved complete remission after early intervention of combined immunosuppressive therapy without residual pulmonary interstitial changes.
引用
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页数:6
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