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Case Report: Rapidly Progressive Interstitial Lung Disease in A Pregnant Patient With Anti-Melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis
被引:6
|作者:
Chen, Cuihong
[1
]
Chen, Yulan
[1
]
Huang, Qin
[1
]
Hu, Qiu
[1
]
Hong, Xiaoping
[1
]
机构:
[1] Southern Univ Sci & Technol, Affiliated Hosp 1, Jinan Univ, Clin Med Coll 2,Dept Rheumatol & Immunol,Shenzhen, Shenzhen, Peoples R China
来源:
关键词:
clinically amyopathic dermatomyositis;
anti-melanoma differentiation-associated gene 5;
rapidly progressive interstitial lung disease;
pregnancy;
treatment;
CLINICALLY AMYOPATHIC DERMATOMYOSITIS;
ANTI-MDA5;
ANTIBODY;
AUTOANTIBODIES;
THERAPY;
RISK;
D O I:
10.3389/fimmu.2021.625495
中图分类号:
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号:
100102 ;
摘要:
Dermatomyositis occurs extremely rarely during pregnancy. A number of studies in the published literature have documented how the outcome of pregnancy is poor for both mother and fetus. The present case study reports on a patient who was diagnosed with clinically amyopathic dermatomyositis complicated by interstitial lung disease during pregnancy, and was successfully treated with a combined immunosuppressant regimen. To the best of the authors' knowledge, this is the first case study detailing how a pregnant woman with clinically amyopathic dermatomyositis with positive anti-melanoma differentiation-associated gene 5 antibody achieved complete remission after early intervention of combined immunosuppressive therapy without residual pulmonary interstitial changes.
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页数:6
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