Mini-Review of Poloxamer as a Biocompatible Polymer for Advanced Drug Delivery

被引：4
|
作者：
Nugraha, Dwianto Harry [1 ,3 ,4 ]
Anggadiredja, Kusnandar [2 ]
Rachmawati, Heni [1 ]
机构：
[1] Inst Teknol Bandung, Sch Pharm, Dept Pharmaceut, Bandung, Indonesia
[2] Inst Teknol Bandung, Sch Pharm, Dept Pharmacol & Clin Pharm, Bandung, Indonesia
[3] PT Dankos Farma, Dept Formulat, Res & Dev Div, Jakarta, Indonesia
[4] Inst Teknol Bandung, Kelompok Keilmuan Farmaset Sekolah Farm, Labtek 7,Jl Ganesa 10, Kota Bandung 40132, Jawa Barat, Indonesia
来源：
BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2022年 / 58卷
关键词：
Poloxamer; Biocompatible; Physicochemical Modification and Biological Response  Modification; DISSOLUTION RATE ENHANCEMENT; BRAIN-BARRIER DAMAGE; IN-VITRO; CELLULAR UPTAKE; BLOCK-COPOLYMERS; NANOPARTICLES; STABILITY; MICELLES; SOLUBILITY; MECHANISMS;
D O I：
10.1590/s2175-97902022e21125
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Poloxamer is a biocompatible polymer that has already been approved by the US FDA for multiple applications. Poloxamer itself has many grades and functional categories that enable the improvement of both physicochemical and biological properties of drugs. In this minireview, the functional properties of poloxamer for physicochemical modification, such as solubility and stability, and biological response modification, such as neuroprotection, cell apoptosis, efflux pump modification, membrane cell modification, and cellular uptake, are discussed to provide a broader understanding to assist the development of poloxamer-based formulations.
引用
收藏
页数：8
相关论文
共 50 条
  • [21] Hydroxyapatite-polymer nanocomposites for drug delivery applications: A mini review
    Behmagham, Farnaz
    Dhiaa, Shahad Mohammed
    Hussein, Abbas Hameed Abdul
    Radi, Usama Kadem
    Mushtaq, Hiba
    Idan, Ameer Hassan
    Vessally, Esmail
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY REPORTS, 2024, 12
  • [22] Ethosomes as delivery system for treatment of melanoma: a mini-review
    Grossi, Livia Nascimento
    Braz, Wilson Rodrigues
    da Silva, Natalia Prado
    Cazarim, Estael Luzia Coelho Cruz
    Palmieri, Miguel Gontijo Siqueira
    Tavares, Guilherme Diniz
    Pittella, Frederico
    ONCOLOGIE, 2023, 25 (05) : 455 - 459
  • [23] A mini-review on MXenes as versatile substrate for advanced sensors
    Soomro, Razium Ali
    Jawaid, Sana
    Zhu, Qizhen
    Abbas, Zaheer
    Xu, Bin
    CHINESE CHEMICAL LETTERS, 2020, 31 (04) : 922 - 930
  • [24] A mini-review on MXenes as versatile substrate for advanced sensors
    Razium Ali Soomro
    Sana Jawaid
    Qizhen Zhu
    Zaheer Abbas
    Bin Xu
    ChineseChemicalLetters, 2020, 31 (04) : 922 - 930
  • [25] Biomimetic Calcium Phosphate Coating as a Drug Delivery Vehicle for Bone Tissue Engineering: A Mini-Review
    Lin, Xingnan
    Chen, Jiping
    Liao, Ying
    Pathak, Janak Lal
    Li, Huang
    Liu, Yuelian
    COATINGS, 2020, 10 (11) : 1 - 19
  • [26] Progresses in targeted drug delivery systems using chitosan nanoparticles in cancer therapy: A mini-review
    Rostami, Elham
    JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2020, 58
  • [27] Stimuli-Responsive Core-Shell Electrospun Nanofibers for Drug Delivery: A Mini-Review
    Xie, Songpei
    Zhang, Jing
    Orf, Chase
    Byars, Allison
    Zhu, Mengfan
    JOURNAL OF APPLIED POLYMER SCIENCE, 2025,
  • [28] Nanocellulose: A mini-review on types and use in drug delivery systems (vol 2, 100031, 2021)
    Raghav, N.
    CARBOHYDRATE POLYMER TECHNOLOGIES AND APPLICATIONS, 2021, 2
  • [29] AI-driven innovations in smart multifunctional nanocarriers for drug and gene delivery: A mini-review
    Noury, Hamid
    Rahdar, Abbas
    Ferreira, Luiz Fernando Romanholo
    Jamalpoor, Zahra
    CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2025, 210
  • [30] A mini-review on drug delivery through wafer technology: Formulation and manufacturing of buccal and oral lyophilizates
    Ribeiro Costa, Juliana Souza
    Cruvinel, Karen de Oliveira
    Oliveira-Nascimento, Laura
    JOURNAL OF ADVANCED RESEARCH, 2019, 20 : 33 - 41
12345