A simple and versatile method to determine the enantiomeric purity of Diels-Alder adducts

被引：7
|
作者：
Hall, A
Harris, LD
Jones, CL
Jenkins, RL
Tomkinson, NCO
机构：
[1] Univ Wales Coll Cardiff, Dept Chem, Cardiff CF10 3TB, S Glam, Wales
[2] GlaxoSmithKline Res & Dev Ltd, Welwyn Garden City AL6 9AR, Herts, England
来源：
TETRAHEDRON LETTERS | 2003年 / 44卷 / 01期
关键词：
D O I：
10.1016/S0040-4039(02)02454-1
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The determination of the enantiomeric purity of Diels-Alder adducts derived from cyclopentadiene and a series of electron-deficient dienophiles is conveniently achieved by HPLC analysis on their 2,4-dinitrophenylhydrazine derivatives formed in one-pot directly from the cycloaddition reaction. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：111 / 114
页数：4
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