Intramolecular [3+2]-cycloaddition of salicylaldehydes-based cyclic azomethine imines to access novel tetrahydrochromeno[4,3-c] pyrazolo[1,2-a]pyrazol-9-ones

被引：3
|
作者：
Wu, Mei-Chun [1 ,2 ]
Xia, Peng-Ju [1 ]
Hu, Yuan-Zhuo [1 ]
Ye, Zhi-Peng [1 ]
Chen, Kai [1 ]
Xiang, Hao-Yue [1 ]
Yang, Hua [1 ]
机构：
[1] Cent South Univ, Coll Chem & Chem Engn, Changsha 410083, Peoples R China
[2] Huaihua Univ, Coll Chem & Mat Engn, Huaihua 418008, Peoples R China
来源：
TETRAHEDRON | 2021年 / 83卷
基金：
中国国家自然科学基金;
关键词：
Intramolecular; 3+2]-cycloaddition; Tetracyclic skeleton;
D O I：
10.1016/j.tet.2021.131992
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient intramolecular [3 + 2]-cycloaddition of in situ-formed salicylaldehyde-based N,N'-cyclic azomethine imines was successfully developed to access novel tetracyclic skeleton bearing three contiguous stereogenic centres. This established protocol features high functional-group tolerance, excellent chemical yields, good diastereoselectivities, and variable reaction conditions. (C) 2021 Elsevier Ltd. All rights reserved.
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页数：5
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