Microwave-promoted ring opening reaction of azalactones

被引：12
|
作者：
Valdes, Ricardo H.
Aranda, Donato A. G.
Alvarez, Heiddy M.
Antunes, Octavio A. C.
机构：
[1] Univ Fed Rio de Janeiro, Inst Quim, BR-21945970 Rio de Janeiro, Brazil
[2] Univ Fed Rio de Janeiro, Escola Quim, BR-21945970 Rio de Janeiro, Brazil
来源：
LETTERS IN ORGANIC CHEMISTRY | 2007年 / 4卷 / 01期
关键词：
alpha; beta-dehydroarnino amides; azalactones; ring opening; microwave irradiation;
D O I：
10.2174/157017807780037360
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
alpha,beta-Dehydroamino amides are important intermediates for the synthesis of biologically active molecules. A rapid procedure is reported for the synthesis of alpha,beta-dehydroamino amides from azalactones under MW radiation. Azalactones were produced via Erlenmeyer reaction and submitted to ring opening reactions under MW during 15-30 min. Over 90% yields were obtained.
引用
收藏
页码：35 / 38
页数：4
相关论文
共 50 条
  • [21] Microwave-promoted synthesis of chiral pyridinium salts
    Viana, GHR
    Santos, IC
    Alves, RB
    Gil, L
    Marazano, C
    Gil, RPF
    TETRAHEDRON LETTERS, 2005, 46 (45) : 7773 - 7776
  • [22] Watching microwave-promoted chemistry: reaction monitoring using a digital camera interfaced with a scientific microwave apparatus
    Bowman, Matthew D.
    Leadbeater, Nicholas E.
    Barnard, T. Michael
    TETRAHEDRON LETTERS, 2008, 49 (01) : 195 - 198
  • [23] AN IMPROVED APPROACH TO N-SUBSTITUTED MALEIMIDES AND PHTHALIMIDES BY MICROWAVE-PROMOTED MITSUNOBU REACTION
    Mayer, Christoph D.
    Kehrel, Marcus
    Bracher, Franz
    ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 2008, 40 (06) : 574 - 579
  • [24] An Efficient Synthesis of Oxygen-Bridged Spirooxindoles via Microwave-Promoted Multicomponent Reaction
    Shi, Yaojing
    Zhao, Hua
    Zhao, Yufen
    MOLECULES, 2023, 28 (08):
  • [25] Microwave-promoted tandem reactions for the synthesis of bicyclic γ-lactams
    McGonagle, Fiona I.
    Brown, Lindsay
    Cooke, Andrew
    Sutherland, Andrew
    TETRAHEDRON LETTERS, 2011, 52 (18) : 2330 - 2332
  • [26] Scaling-up microwave-promoted organic transformations
    Williams, Victoria A.
    Bowman, Matthew D.
    Leadbeater, Nicholas E.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 234
  • [27] Rapid microwave-promoted synthesis of new sulfonylmethylbenzothiazoles in water
    Gellis, A
    Boufatah, N
    Vanelle, P
    GREEN CHEMISTRY, 2006, 8 (05) : 483 - 487
  • [28] Undergraduate student research in microwave-promoted organic syntheses
    Armstrong, Douglas
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 239
  • [29] Microwave-promoted Beller's synthesis of substituted phthalates
    Yang, YY
    Shou, WG
    Wang, YG
    SYNTHETIC COMMUNICATIONS, 2006, 36 (10) : 1383 - 1390
  • [30] Microwave-promoted palladium-catalyzed coupling reactions
    Larhed, M
    Hallberg, A
    JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (26): : 9582 - 9584
12345