Cardiac resurrection after bone-marrow-derived mononuclear cell transplantation during left ventricular assist device support

被引：17
|
作者：
Gojo, Satoshi
Kyo, Shunei
Nishimura, Shigeyuki
Komiyama, Nobuyuki
Kawai, Nobutaka
Bessho, Masami
Sato, Hiroshige
Asakura, Toshihisa
Nishimura, Motonobu
Ikebuchi, Kenji
机构：
[1] Saitama Med Ctr, Dept Cardiovasc Surg, Kagagoe, Saitama 3508550, Japan
[2] Saitama Med Sch, Dept Cardiovasc Surg, Kagagoe, Saitama, Japan
[3] Saitama Med Sch, Dept Cardiol, Kagagoe, Saitama, Japan
[4] Saitama Med Sch, Dept Hematol, Kagagoe, Saitama, Japan
[5] Saitama Med Sch, Dept Transfus & Cell Therapy, Kagagoe, Saitama, Japan
来源：
ANNALS OF THORACIC SURGERY | 2007年 / 83卷 / 02期
关键词：
D O I：
10.1016/j.athoracsur.2006.06.074
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We describe a novel therapy of mononuclear cell transplantation combined with a left ventricular assist device (LVAD) for severe ischemic heart failure. Significant myocardial recovery by the LVAD rarely occurs in the severely failing heart. We undertook successful mononuclear cell transplantation in a patient who sustained an acute myocardial infarction that had resulted in the LVAD therapy. The heart regained good function after cell transplantation, and the LVAD was explanted 6 weeks later. These results suggest that this novel therapy could be an alternative to cardiac transplantation for severe ischemic heart failure.
引用
收藏
页码：661 / 662
页数：2
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