Succinic acid-producing Anaerobiospirillum succiniciproducens was anaerobically grown in glucose-fed continuous cultures using glucose as a carbon source, and the metabolic flexibility of A. succiniciproducens in response to varying glucose concentrations and dilution rates was examined. Both succinic acid (SA) and acetic acid (AA) formation was growth-associated, and their growth-rate-related coefficients (K(SA/X), K(AA/X)) and nongrowth-rate-related coefficients (K'(SA/X), K'(AA/X)) were slightly influenced by glucose concentrations. A high glucose concentration (38 g/l) and high growth rate (0.63 h(-1)) did not induce by-product formation.
机构:
MIT, Dept Biol, Cambridge, MA 02139 USA
Beuth Hsch Tech Berlin, Dept Biotechnol, D-13353 Berlin, GermanyMIT, Dept Biol, Cambridge, MA 02139 USA
Grunwald, Stephan
Mottet, Alexis
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机构:
Univ Toulouse, INSA, UPS, INP,LISBP, F-31077 Toulouse, France
INRA, Ingn Syst Biol & Proc UMR792, F-31400 Toulouse, France
CNRS, UMR5504, F-31400 Toulouse, FranceMIT, Dept Biol, Cambridge, MA 02139 USA
Mottet, Alexis
Grousseau, Estelle
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机构:
MIT, Dept Biol, Cambridge, MA 02139 USA
Univ Toulouse, INSA, UPS, INP,LISBP, F-31077 Toulouse, France
INRA, Ingn Syst Biol & Proc UMR792, F-31400 Toulouse, France
CNRS, UMR5504, F-31400 Toulouse, FranceMIT, Dept Biol, Cambridge, MA 02139 USA
Grousseau, Estelle
Plassmeier, Jens K.
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机构:
MIT, Dept Biol, Cambridge, MA 02139 USAMIT, Dept Biol, Cambridge, MA 02139 USA
Plassmeier, Jens K.
Popovic, Milan K.
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机构:
Beuth Hsch Tech Berlin, Dept Biotechnol, D-13353 Berlin, GermanyMIT, Dept Biol, Cambridge, MA 02139 USA
Popovic, Milan K.
Uribelarrea, Jean-Louis
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机构:
Univ Toulouse, INSA, UPS, INP,LISBP, F-31077 Toulouse, France
INRA, Ingn Syst Biol & Proc UMR792, F-31400 Toulouse, France
CNRS, UMR5504, F-31400 Toulouse, FranceMIT, Dept Biol, Cambridge, MA 02139 USA
Uribelarrea, Jean-Louis
Gorret, Nathalie
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机构:
Univ Toulouse, INSA, UPS, INP,LISBP, F-31077 Toulouse, France
INRA, Ingn Syst Biol & Proc UMR792, F-31400 Toulouse, France
CNRS, UMR5504, F-31400 Toulouse, FranceMIT, Dept Biol, Cambridge, MA 02139 USA
Gorret, Nathalie
Guillouet, Stephane E.
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机构:
Univ Toulouse, INSA, UPS, INP,LISBP, F-31077 Toulouse, France
INRA, Ingn Syst Biol & Proc UMR792, F-31400 Toulouse, France
CNRS, UMR5504, F-31400 Toulouse, FranceMIT, Dept Biol, Cambridge, MA 02139 USA
Guillouet, Stephane E.
Sinskey, Anthony
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h-index: 0
机构:
MIT, Dept Biol, Cambridge, MA 02139 USA
MIT, Div Hlth Sci & Technol, Cambridge, MA 02139 USA
MIT, Engn Syst Div, Cambridge, MA 02139 USAMIT, Dept Biol, Cambridge, MA 02139 USA
机构:Korea Advanced Institute of Science and Technology,Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical & Biomolecular Engineering and BioProcess Engineering Research Center
P. C. Lee
S. Y. Lee
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机构:Korea Advanced Institute of Science and Technology,Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical & Biomolecular Engineering and BioProcess Engineering Research Center
S. Y. Lee
S. H. Hong
论文数: 0引用数: 0
h-index: 0
机构:Korea Advanced Institute of Science and Technology,Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical & Biomolecular Engineering and BioProcess Engineering Research Center
S. H. Hong
H. N. Chang
论文数: 0引用数: 0
h-index: 0
机构:Korea Advanced Institute of Science and Technology,Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical & Biomolecular Engineering and BioProcess Engineering Research Center
H. N. Chang
Bioprocess and Biosystems Engineering,
2003,
26
: 63
-
67
机构:
Korea Res Inst Chem Technol, Reliabil Assessment Ctr, Daejeon 34114, South KoreaBaqai Med Univ, Baqai Inst Pharmaceut Sci, Dept Pharmaceut, Karachi 75340, Pakistan
Heo, Kyuyoung
Na, Jun-Hee
论文数: 0引用数: 0
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机构:
Chungnam Natl Univ, Dept Convergence Syst Engn, Daejeon 34134, South KoreaBaqai Med Univ, Baqai Inst Pharmaceut Sci, Dept Pharmaceut, Karachi 75340, Pakistan