Metabolites from the Sea Hare Aplysia fasciata

被引：12

作者：

Ioannou, Efstathia ^{[1
]}

Nappo, Michela ^{[2
]}

Avila, Conxita ^{[2
]}

Vagias, Constantinos ^{[1
]}

Roussis, Vassilios ^{[1
]}

机构：

[1] Univ Athens, Sch Pharm, Dept Pharmacognosy & Chem Nat Prod, GR-15771 Athens, Greece

[2] Univ Barcelona, Fac Biol, Dept Anim Biol Invertebrates, E-08028 Barcelona, Catalonia, Spain

来源：

JOURNAL OF NATURAL PRODUCTS | 2009年 / 72卷 / 09期

关键词：

MARINE NATURAL-PRODUCTS; ALGA LAURENCIA-OBTUSA; ABSOLUTE-CONFIGURATION; SESQUITERPENES; PINNATIFIDA;

D O I：

10.1021/np900298a

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Examination of the digestive and hermaphroditic glands' organic extract of the sea hare Aplysia fasciata yielded 16 metabolites, including eight sesquiterpenes, three diterpenes, and five C-15-acetogenins. Among them, three sesquiterpenes, 6-hydroxy-1-brasilene (1), epibrasilenol acetate (2), and 6-epi-beta-snyderol (3), one acetogenin, (3Z,9z)-7-chloro-6-hydroxy-12-oxo-pentadeca-3,9-dien- 1-yne (4), and one diterpene, 16-acetoxy-15-bromo-7-hydroxy-9(11)-parguerene (5), are new natural products. The structure elucidation and the assignment of the relative configurations of the isolated natural products were established on the basis of extensive analyses of their spectroscopic data (NMR, MS, IR).

引用

页码：1716 / 1719

页数：4

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