Palladium-Catalyzed Trifluoromethylthiolation of Chelation-Assisted C-H Bonds

被引：13
|
作者：
Kesavan, Arunachalam [1 ]
Chaitanya, Manthena [1 ]
Anbarasan, Pazhamalai [1 ]
机构：
[1] Indian Inst Technol Madras, Dept Chem, Madras 600036, Tamil Nadu, India
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2018年 / 2018卷 / 25期
关键词：
Trifluoromethylthiolation; C-H bond functionalization; Palladium; Arylpyridines; BORONIC ACIDS; SELECTIVE TRIFLUOROMETHYLTHIOLATION; OXIDATIVE TRIFLUOROMETHYLTHIOLATION; SODIUM TRIFLUOROMETHANESULFINATE; ARYL CHLORIDES; INDOLES; CYANATION; LIGAND; MILD; THIOLS;
D O I：
10.1002/ejoc.201800451
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient palladium-catalyzed trifluoromethylthiolation of chelation-assisted C-H bonds has been accomplished by employing a readily accessible trifluoromethylthiolating reagent. The reaction tolerates various directing groups and functional groups and allows the access to diverse trifluoromethylthiolated arenes in good yield. A plausible mechanism was proposed based on preliminary mechanistic investigations.
引用
收藏
页码：3276 / 3279
页数：4
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