Cytotoxicity of cyanoacrylate adhesives to cultured tendon cells

被引:24
|
作者
Evans, CE [1 ]
Lees, GC [1 ]
Trail, IA [1 ]
机构
[1] Univ Manchester, Dept Orthopaed Surg, Manchester M13 9PL, Lancs, England
来源
关键词
D O I
10.1054/jhsb.1999.0279
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
The in vitro cytotoxicity of four cyanoacrylate adhesives,vas tested using cultures of cells derived from human tendons. All four mere found to be cytotoxic, even at concentrations as low as 1.7%, over the experimental period of up to 18 weeks, This study shows that such adhesives in their present state may not be suitable for re-joining cut tendons as their initial and long-term toxicity may hinder the slow healing process of tendons.
引用
收藏
页码:658 / 661
页数:4
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