Four homoverrucosane-type diterpenes from the marine sponge Halichondria sp

被引：4

作者：

Tian, Yong-Qi ^{[2
]}

Gu, Bin-Bin ^{[1
]}

Jiao, Wei-Hua ^{[1
]}

Lin, Hou-Wen ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Ren Ji Hosp, Res Ctr Marine Drugs, Sch Med,Dept Pharm,State Key Lab Oncogenes & Rela, Shanghai 200127, Peoples R China

[2] Fuzhou Univ, Coll Biol Sci & Engn, Fuzhou 350116, Peoples R China

来源：

TETRAHEDRON | 2020年 / 76卷 / 50期

关键词：

Halichondria sp. diterpenes; ECD spectroscopy; Cytotoxicity; SESQUITERPENE;

D O I：

10.1016/j.tet.2020.131697

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Four new homoverrucosane-type diterpenes (1-4) and two known analogs (5-6) were isolated from the marine sponge Halichondria sp. Their structures including absolute configurations were determined by combination of spectroscopic analyses, theoretical calculations and comparison with data of literatures. The cytotoxicity against human multiple myeloma cell line RPMI-8266 of compounds 1-4 was evaluated, but none showed activity (IC50 > 10 mu M). It was the first report that homoverrucosanes isolated from the marine sponge Halichondria sp. (C) 2020 Published by Elsevier Ltd.

引用

页数：5

共 50 条

[31] PURIFICATION AND CHARACTERIZATION OF A LECTIN FROM A MARINE SPONGE HALICHONDRIA-PANICEA
KAMIYA, H
MURAMOTO, K
GOTO, R
NIPPON SUISAN GAKKAISHI, 1990, 56 (07) : 1159 - 1159
[32] Synthesis of the indole alkaloid isolated from the marine sponge Halichondria melanodocia
Gribble, Gordon W.
Wright, Stephen W.
TETRAHEDRON, 2025, 169
[33] NOVEL, REGIOSELECTIVE ALLYLAMINE CONSTRUCTION - 1ST SYNTHESIS OF GERANYLLINALOISOCYANIDE, A DITERPENE FROM THE MARINE SPONGE, HALICHONDRIA SP
ICHIKAWA, Y
YAMAZAKI, M
ISOBE, M
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1993, (20): : 2429 - 2432
[34] New diterpenes from marine sponge Myrmekioderna styx.
Peng, JN
Hamann, MT
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 222 : U662 - U662
[35] Halicylindramides D and E, antifungal peptides from the marine sponge Halichondria cylindrata
Li, HY
Matsunaga, S
Fusetani, N
JOURNAL OF NATURAL PRODUCTS, 1996, 59 (02): : 163 - 166
[36] HALICYLINDROSIDES, ANTIFUNGAL AND CYTOTOXIC CEREBROSIDES FROM THE MARINE SPONGE HALICHONDRIA-CYLINDRATA
LI, HY
MATSUNAGA, S
FUSETANI, N
TETRAHEDRON, 1995, 51 (08) : 2273 - 2280
[37] ISOLATION OF (Z)-17-TETRACOSENAL FROM THE MARINE SPONGE HALICHONDRIA PANICEA
CARBALLEIRA, NM
CHEMISTRY AND PHYSICS OF LIPIDS, 1986, 39 (04) : 365 - 368
[38] Spongian diterpenes from Chinese marine sponge Spongia officinalis
Han, Guan-Ying
Sun, Dong-Yu
Liang, Lin-Fu
Yao, Li-Gong
Chen, Kai-Xian
Guo, Yue-Wei
FITOTERAPIA, 2018, 127 : 159 - 165
[39] Two Isospongian Diterpenes from the Sponge Luffariella sp.
Faricha, Ana
Ahmadi, Peni
de Voogd, Nicole J.
Tanaka, Junichi
NATURAL PRODUCT COMMUNICATIONS, 2017, 12 (07) : 1011 - 1012
[40] Halichonadins A-D, new sesquiterpenoids from a sponge Halichondria sp.
Ishiyama, H
Hashimoto, A
Fromont, J
Hoshino, Y
Mikami, Y
Kobayashi, J
TETRAHEDRON, 2005, 61 (05) : 1101 - 1105

← 1 2 3 4 5 →