Catalyst-free rapid synthesis of benzo[4,5]imidazo[1,2-a]-pyrimidine-3-carboxamides via four-component coupling in one pot

被引：8

作者：

Shaabani, Ahmad ^{[1
]}

Seyyedhamzeh, Mozhdeh ^{[1
]}

Ganji, Nasim ^{[1
]}

Seik Weng Ng ^{[2
]}

机构：

[1] Shahid Beheshti Univ, Dept Chem, GC, Tehran, Iran

[2] Univ Malaya, Dept Chem, Kuala Lumpur 50603, Malaysia

来源：

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY | 2014年 / 11卷 / 02期

关键词：

Catalyst-free; Multicomponent reaction; 2,2,6-Trimethyl-4H-1,3-dioxin-4-one; 1H-Benzo[d]imidazol-2-amine; DIVERSITY-ORIENTED SYNTHESIS; CALCIUM-CHANNEL BLOCKERS; MULTICOMPONENT REACTIONS; SOLVENT-FREE; ACID-ESTERS;

D O I：

10.1007/s13738-013-0321-6

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new class of fused tricyclic benzo[4,5]imidazo[1,2-a]-pyrimidine-3-carboxamide derivatives was synthesized via an environmentally benign one pot sequential four-component condensation reaction of an amine, 2,2,6-trimethyl-4H-1,3-dioxin-4-one, an aldehyde and 1H-benzo[d]imidazol-2-amine without using catalyst in good yields.

引用

页码：481 / 487

页数：7

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