Clinical Assessment of Cognitive Decline in Adults with Down Syndrome

被引：21

作者：

Sabbagh, Marwan ^{[1
]}

Edgin, Jamie ^{[2
,3
]}

机构：

[1] Banner Sun Hlth Res Inst, Cleo Roberts Ctr Clin Res, Sun City, AZ 85351 USA

[2] Univ Arizona, Dept Psychol, Tucson, AZ USA

[3] Univ Arizona, Sonoran Univ Ctr Excellence Dev Disabil, Tucson, AZ USA

来源：

CURRENT ALZHEIMER RESEARCH | 2016年 / 13卷 / 01期

关键词：

Alzheimer's disease; assessment; decline; dementia; down syndrome; neuropsychological; sleep; POSITRON-EMISSION-TOMOGRAPHY; OBSTRUCTIVE SLEEP-APNEA; IN-VIVO MRI; ALZHEIMERS-DISEASE; INTELLECTUAL DISABILITY; BEHAVIOR CHANGES; AMYLOID-BETA; TEST BATTERY; DEMENTIA; AGE;

D O I：

10.2174/1567205012666150921095724

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Down syndrome is an intellectual disability requiring periodic monitoring of cognition given the near universal presence of Alzheimer's Disease related neuropathology and high rates of dementia in middle adulthood. We review current approaches to detecting decline in this population, including informant-based measures, dementia screening tools, and neuroimaging techniques. The challenges for detecting decline in this group are discussed, including the need to take into account premorbid cognitive function as well as medical comorbidity.

引用

页码：30 / 34

页数：5

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