Clinical Assessment of Cognitive Decline in Adults with Down Syndrome

被引:21
|
作者
Sabbagh, Marwan [1 ]
Edgin, Jamie [2 ,3 ]
机构
[1] Banner Sun Hlth Res Inst, Cleo Roberts Ctr Clin Res, Sun City, AZ 85351 USA
[2] Univ Arizona, Dept Psychol, Tucson, AZ USA
[3] Univ Arizona, Sonoran Univ Ctr Excellence Dev Disabil, Tucson, AZ USA
关键词
Alzheimer's disease; assessment; decline; dementia; down syndrome; neuropsychological; sleep; POSITRON-EMISSION-TOMOGRAPHY; OBSTRUCTIVE SLEEP-APNEA; IN-VIVO MRI; ALZHEIMERS-DISEASE; INTELLECTUAL DISABILITY; BEHAVIOR CHANGES; AMYLOID-BETA; TEST BATTERY; DEMENTIA; AGE;
D O I
10.2174/1567205012666150921095724
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Down syndrome is an intellectual disability requiring periodic monitoring of cognition given the near universal presence of Alzheimer's Disease related neuropathology and high rates of dementia in middle adulthood. We review current approaches to detecting decline in this population, including informant-based measures, dementia screening tools, and neuroimaging techniques. The challenges for detecting decline in this group are discussed, including the need to take into account premorbid cognitive function as well as medical comorbidity.
引用
收藏
页码:30 / 34
页数:5
相关论文
共 50 条
  • [1] Assessment of decline in adults with Down syndrome
    Devenny, DA
    Kittler, P
    Krinsky-McHale, SJ
    JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, 2000, 44 : 264 - 265
  • [2] Language skills as a predictor of cognitive decline in adults with Down syndrome
    Pulsifer, Margaret B.
    Evans, Casey L.
    Hom, Christy
    Krinsky-McHale, Sharon J.
    Silverman, Wayne
    Lai, Florence
    Lott, Ira
    Schupf, Nicole
    Wen, Jiyang
    Rosas, H. Diana
    ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING, 2020, 12 (01)
  • [3] Sequence of cognitive decline in dementia in adults with Down's syndrome
    Devenny, DA
    Krinsky-McHale, SJ
    Sersen, G
    Silverman, WP
    JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, 2000, 44 : 654 - 665
  • [4] Cognitive decline in Down syndrome
    Margallo-Lana, ML
    Ballard, C
    Morris, C
    Kay, D
    Tyrer, S
    Moore, B
    ARCHIVES OF NEUROLOGY, 2003, 60 (07) : 1024 - 1024
  • [5] Validating the Cognitive Scale for Down Syndrome (CS-DS) to Detect Longitudinal Cognitive Decline in Adults With Down Syndrome
    Startin, Carla M.
    Lowe, Bryony
    Hamburg, Sarah
    Hithersay, Rosalyn
    Strydom, Andre
    Fisher, Elizabeth
    Nizetic, Dean
    Hardy, John
    Tybulewicz, Victor
    Karmiloff-Smith, Annette
    FRONTIERS IN PSYCHIATRY, 2019, 10
  • [6] COGNITIVE DECLINE AND DEMENTIA IN DOWN SYNDROME
    Strydom, A.
    JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, 2016, 60 (09) : 837 - 837
  • [7] Cognitive decline and dementia in Down syndrome
    Hithersay, Rosalyn
    Hamburg, Sarah
    Knight, Bernice
    Strydom, Andre
    CURRENT OPINION IN PSYCHIATRY, 2017, 30 (02) : 102 - 107
  • [8] Bereavement and behavioral changes as risk factors for cognitive decline in adults with Down syndrome
    Fonseca, Luciana Mascarenhas
    de Oliveira, Melaine Cristina
    de Figueiredo Ferreira Guilhoto, Aura Maria
    Cavalheiro, Esper Abrao
    Bottino, Cassio M. C.
    NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2014, 10 : 2209 - 2219
  • [9] Screening for Dementia and Cognitive Decline in Adults With Down Syndrome A Novel Approach Using the Informant Questionnaire on Cognitive Decline in the Elderly
    Mattar, Guilherme Prado
    Uchida, Ricardo R.
    Haddad, Glenda G.
    Shiozawa, Pedro
    da Silva, Maria de Fatima Reboucas
    Hoexter, Marcelo Q.
    Busatto, Geraldo F.
    Bottino, Cassio M. de Campos
    Fonseca, Luciana M.
    Forlenza, Orestes, V
    ALZHEIMER DISEASE & ASSOCIATED DISORDERS, 2022, 36 (02): : 162 - 167
  • [10] Factors associated with cognitive decline in Down syndrome
    Tyrer, SP
    Margallo-Lana, ML
    Moore, PD
    Kay, DW
    Perry, RH
    Berney, TP
    Morris, C
    JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, 2000, 44 : 496 - 496