FDG-PET in suspected dementia with Lewy bodies: a case report

被引：3
|
作者：
Suantio, Astrid Melani [1 ]
Hian Liang Huang [2 ]
Kwok, Cecilia Sze Nga [3 ]
Teo, Darren Cheng Han [4 ]
Minh Ha Nguyen [5 ]
机构：
[1] Sengkang Gen Hosp, Dept Internal Med, Geriatr Med, E Way, Sengkang 544886, Singapore
[2] Singapore Gen Hosp, Dept Nucl Med & Mol Imaging, Outram Rd, Singapore 169608, Singapore
[3] Singapore Gen Hosp, Dept Psychiat, Outram Rd, Singapore 169608, Singapore
[4] MOH Holdings Pte Ltd, Singhlth Residency Program, Singapore 099253, Singapore
[5] Singapore Gen Hosp, Dept Geriatr Med, Outram Rd, Singapore 169608, Singapore
来源：
BMC GERIATRICS | 2019年 / 19卷 / 1期
关键词：
Dementia with Lewy bodies; FDG-PET; Imaging; Rivastigmine; DIAGNOSIS; MANAGEMENT;
D O I：
10.1186/s12877-019-1166-3
中图分类号：
R592 [老年病学]; C [社会科学总论];
学科分类号：
03 ; 0303 ; 100203 ;
摘要：
BackgroundDementia with Lewy bodies (DLB) is still underdiagnosed or mistaken for other types of neurodegenerative diseases. Biomarkers such as 18-Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) can be helpful.Case presentationA 72-year-old gentleman presented with postural hypotension, hallucination, Parkinsonism and recurrent falls. He also had rapidly progressing cognitive impairment. CT and MRI brain showed atrophy of the frontal lobes with preservation of the hippocampi. FDG-PET was suggestive of DLB. He was subsequently treated with Rivastigmine, with significant improvement of his symptoms.ConclusionThis case highlights the challenges in diagnosis of an elderly patient with DLB, the use of neuro-imaging as a diagnostic biomarker, the avoidance of the use of antipsychotic and the response to pharmacological treatment with Rivastigmine after a probable diagnosis of DLB.
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页数：5
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