Silica gel-promoted practical synthesis of oxindole-nitrones from diazooxindoles and nitrosoarenes under solvent-free conditions

被引：18
|
作者：
Zhang, Yun-Hao [1 ]
Wu, Ming-Yue [2 ]
Huang, Wen-Cai [1 ]
机构：
[1] Sichuan Univ, Sch Chem Engn, Dept Pharmaceut & Bioengn, Chengdu 610065, Peoples R China
[2] South Univ Sci & Technol China, Dept Chem, Shenzhen 518055, Peoples R China
来源：
RSC ADVANCES | 2015年 / 5卷 / 128期
关键词：
1,3-DIPOLAR CYCLOADDITION REACTIONS; CHIRAL BRONSTED ACID; DIELS-ALDER REACTION; N-ARYL KETONITRONES; HIGHLY EFFICIENT; FACILE; CATALYSIS; ALDEHYDES; SPIROOXINDOLES; CONSTRUCTION;
D O I：
10.1039/c5ra21874h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A practical method for the synthesis of oxindole-nitrones promoted by silica gel was developed with good results. The protocol is environmentally friendly as the reaction proceeds under solvent-free conditions with broad substrate scope, and high selectivity and chemical yield, and the silica gel can be quantitatively recovered and reused multiple times.
引用
收藏
页码：105825 / 105828
页数：4
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