A survival model generalized to regression learning algorithms

被引:5
|
作者
Guan, Yuanfang [1 ,2 ]
Li, Hongyang [1 ]
Yi, Daiyao [3 ]
Zhang, Dongdong [4 ]
Yin, Changchang [5 ]
Li, Keyu [1 ]
Zhang, Ping [4 ,5 ]
机构
[1] Univ Michigan, Dept Computat Med & Bioinformat, Michigan Med, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Dept Internal Med, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Dept Biomed Engn, Michigan Med, Ann Arbor, MI 48109 USA
[4] Ohio State Univ, Dept Biomed Informat, Columbus, OH 43210 USA
[5] Ohio State Univ, Dept Comp Sci & Engn, Columbus, OH 43210 USA
来源
NATURE COMPUTATIONAL SCIENCE | 2021年 / 1卷 / 06期
关键词
Artificial intelligence technologies - Clinical informatics - Convolutional neural network - ITS applications - Model method - Pathological images - Prediction problem - Statistic modeling - Survival model - Survival prediction;
D O I
10.1038/s43588-021-00083-2
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Survival prediction is an important problem that is encountered widely in industry and medicine. Despite the explosion of artificial intelligence technologies, no uniformed method allows the application of any type of regression learning algorithm to a survival prediction problem. Here, we present a statistical modeling method that is generalized to all types of regression learning algorithm, including deep learning. We present its empirical advantage when it is applied to traditional survival problems. We demonstrate its expanded applications in different types of regression learning algorithm, such as gradient boosted trees, convolutional neural networks and recurrent neural networks. Additionally, we demonstrate its application in clinical informatic data, pathological images and the hardware industry. We expect that this algorithm will be widely applicable for diverse types of survival data, including discrete data types and those suitable for deep learning such as those with time or spatial continuity.
引用
收藏
页码:433 / 440
页数:8
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