Three-dimensional cardiac cine magnetic resonance imaging with an ultrasmall superparamagnetic iron oxide blood pool agent (NC100150)

被引:0
|
作者
Amano, Y [1 ]
Herfkens, RJ [1 ]
Shifrin, RY [1 ]
Alley, MT [1 ]
Pelc, NJ [1 ]
机构
[1] Stanford Univ, Sch Med, Lucas MRS Ctr, Dept Radiol, Stanford, CA 94305 USA
来源
JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 2000年 / 11卷 / 02期
关键词
three-dimensional MRI; cardiac MRI; myocardial motion; cardiac valves; ultrasmall superparamagnetic iron oxide;
D O I
10.1002/(SICI)1522-2586(200002)11:2<81::AID-JMRI2>3.0.CO;2-N
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
The purpose of this study was to assess image quality of three-dimensional (3D) cardiac cine magnetic resonance (MR) imaging before and after administration of a T1-shortening ultrasmall superparamagnetic iron oxide blood pool agent (NC100150), 3D cardiac cine MR imaging was performed in 13 volunteers using a radiofrequency-spoiled cardiac-gated 3D cine gradient-echo sequence with short repetition and echo times, Compared with precontrast images, postcontrast images showed no enhancement in fat and skeletal muscle, moderate enhancement in myocardium, and significant enhancement in ventricular cavity. After contrast injection, the signal ratio of the ventricular chamber to the myocardium significantly increased, and dramatic Improvements were seen in the quality of the cineangiographic images and the depiction of cardiac valves. This quantitative study has shown that 3D cardiac cine MR imaging using a blood pool agent provided MR ventriculography and cineangiography with excellent image quality. (C) 2000 Wiley-Liss, Inc.
引用
收藏
页码:81 / 86
页数:6
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