A new triterpene from the green walnut husks of Juglans mandshurica Maxim

被引：17

作者：

Zhou, Yuan-Yuan ^{[1
]}

Song, Hong-Juan ^{[1
]}

Guo, Shuang ^{[1
]}

Wang, Ying ^{[1
]}

Gao, Hui-Rui ^{[1
]}

Zhang, Xiao-Juan ^{[2
]}

Sun, Yan-Ping ^{[1
]}

Liu, Yan ^{[1
]}

Yang, Bing-You ^{[1
]}

Kuang, Hai-Xue ^{[1
]}

机构：

[1] Heilongjiang Univ Chinese Med, Coll Pharm, Harbin 150040, Heilongjiang, Peoples R China

[2] Heilongjiang Univ Chinese Med, Acad Res Dept, Harbin 150040, Heilongjiang, Peoples R China

来源：

JOURNAL OF NATURAL MEDICINES | 2019年 / 73卷 / 04期

基金：

黑龙江省自然科学基金; 中国博士后科学基金; 美国国家科学基金会;

关键词：

Juglans mandshurica Maxim; Triterpenes; Cytotoxicity; Antitumor; CYTOTOXICITY; TERPENOIDS; EXTRACTS; MARKERS; LEAF; ROOT;

D O I：

10.1007/s11418-019-01309-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new triterpene named klodorol B (1), together with six known compounds, were isolated from the green walnut husks of Juglans mandshurica Maxim. Their structures were determined using spectroscopic methods on the basis of 1D and 2D NMR, and high-resolution electrospray ionization mass spectrometry. The isolated compounds were evaluated for their cytotoxic activities on human gastric carcinoma (BGC-823), human liver cancer (HepG-2) and human lung cancer (A549) cell lines.

引用

页码：800 / 804

页数：5

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