TIM-1 MUCIN DOMAIN-MUTANT MICE DISPLAY EXACERBATED ATHEROSCLEROSIS

被引:0
|
作者
Douna, H. [1 ]
Smit, V. [1 ]
van Puijvelde, G. [1 ]
Binder, C. [2 ]
Bot, I. [1 ]
Kuchroo, V. [3 ,4 ]
Lichtman, A. [3 ,5 ]
Kuiper, J. [1 ]
Foks, A. [1 ]
机构
[1] LACDR Leiden Univ, Dept BioTherapeut, Leiden, Netherlands
[2] Med Univ Vienna, Dept Lab Med, Vienna, Austria
[3] Brigham & Womens Hosp, 75 Francis St, Boston, MA 02115 USA
[4] Harvard Med Sch, Dept Neurol, Boston, MA 02115 USA
[5] Harvard Med Sch, Dept Pathol, Boston, MA 02115 USA
关键词
D O I
10.1016/j.atherosclerosis.2019.06.074
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
EAS19-0480
引用
收藏
页码:E25 / E26
页数:2
相关论文
共 50 条
  • [31] Inhibition of in vitro and in vivo T cell responses by recombinant human Tim-1 extracellular domain proteins
    Mesri, M
    Smithson, G
    Ghatpande, A
    Chapoval, A
    Shenoy, S
    Boldog, F
    Hackett, C
    Pena, CE
    Burgess, C
    Bendele, A
    Shimkets, RA
    Starling, GC
    INTERNATIONAL IMMUNOLOGY, 2006, 18 (03) : 473 - 484
  • [32] Endogenous Tim-1 promotes severe systemic autoimmunity and renal disease MRL-Faslpr mice
    Nozaki, Yuji
    Kitching, A. Richard
    Akiba, Hisaya
    Yagita, Hideo
    Kinoshita, Koji
    Funauchi, Masanori
    Matsumura, Itaru
    AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2014, 306 (10) : F1210 - F1221
  • [33] TIM-1 Fusion protein (TIM-1/Fc) inhibits hair loss in alopecia areata and augments T cell proliferation and Th2 cytokines in C3H/HeJ mice
    Moss, R. B.
    Sun, G.
    Encinas, J. A.
    Yei, S.
    Rieder, S. E.
    Thomas, M.
    Carlo, D. J.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2006, 126 : 98 - 98
  • [34] Single Nucleotide Variants of the Human TIM-1 IgV Domain with Reduced Ability to Promote Viral Entry into Cells
    Hattori, Takanari
    Saito, Takeshi
    Miyamoto, Hiroko
    Kajihara, Masahiro
    Igarashi, Manabu
    Takada, Ayato
    VIRUSES-BASEL, 2022, 14 (10):
  • [35] Determinants in the Ig Variable Domain of Human HAVCR1 (TIM-1) Are Required To Enhance Hepatitis C Virus Entry
    Kachko, Alla
    Costafreda, Maria Isabel
    Zubkova, Iryna
    Jacques, Jerome
    Takeda, Kazuyo
    Wells, Frances
    Kaplan, Gerardo
    Major, Marian E.
    JOURNAL OF VIROLOGY, 2018, 92 (06)
  • [36] T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation
    de Souza, AJ
    Oriss, TB
    O'Malley, KJ
    Ray, A
    Kane, LP
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (47) : 17113 - 17118
  • [37] The expression of T-cell immunoglobulin and mucin-domain-containing molecule (Tim)-1 and Tim-3 and the relations between Tim and Th response in H. pylori infection and eradication in mice
    Xie, Y.
    Hu, S. J.
    Zhou, N. J.
    Gong, Y. F.
    Liu, D. S.
    Zhou, X. J.
    Lu, N. H.
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2009, 24 : A13 - A14
  • [38] Exacerbated atherosclerosis of double-mutant Lystbeige, LDLr-/- mice is not due solely to altered macrophage function
    Schiller, NK
    Black, AS
    Kubo, N
    Boisvert, WA
    Curtiss, LK
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2002, 22 (05) : A43 - A43
  • [39] The expression of T-cell immunoglobulin and mucin-domain-containing molecule (Tim)-1 and Tim-3 and the relations between Tim and Th response in H. pylori vaccine immune protection in mice
    Xie, Y.
    Gong, Y. F.
    Hu, S. J.
    Zhou, N. J.
    Liu, D. S.
    Zhou, X. J.
    Lu, N. H.
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2009, 24 : A13 - A13
  • [40] Knockdown of T Cell Immunoglobulin and Mucin 1 (Tim-1) Suppresses Glioma Progression Through Inhibition of the Cytokine-PI3K/AKT Pathway
    Zhou, Peng
    Fei, Maoxing
    Han, Yanling
    Zhou, Mengliang
    Wang, Handong
    ONCOTARGETS AND THERAPY, 2020, 13 : 7433 - 7445