A population study of three Y-STR loci by multiplexing in Han population in Chengdu, China

Background: it is necessary to enhance the efficiency of amplification of Y-STR in according with the progress in forensic science. Methods: Using a multiplex of Y-STRs and amplify simultaneously three Y-STRs loci. Results: A multiplexing system of three Y-STR loci (DYS390, DYS391 and DYS393) is successfully established followed by a population genetic study of Han population in Chengdu, China. Conclusions: The diversity of haplotype is 0.8965, the value of discrimination and the chance of exclusion chance is 0.8965 with the standard error 0.0081. This established system is one of the good tools in personal identification and genetic study. (C) 2003 Elsevier B.V. All rights reserved.