The impact of genomics on discovering drugs against infectious diseases

被引：4
|
作者：
Boshoff, Helena I. M. [1 ]
Manjunatha, Ujjini H. [1 ]
机构：
[1] NIA, NIH, TB Res Sect, LIG,NIAID, Bethesda, MD 20852 USA
来源：
MICROBES AND INFECTION | 2006年 / 8卷 / 06期
关键词：
systems biology; genome sequencing; chemical genetics; drug target;
D O I：
10.1016/j.micinf.2005.11.018
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Genomics is accelerating the progress in data generation and interpretation in the global analyses of components of cells, including the spectrum of lipids, RNA, metabolites, proteins, mutational phenotypes or DNA methylation sites. Integration of the knowledge generated by these diverse strategies is predicted to have a tremendous impact on approaches to rational drug discovery against infectious diseases. Published by Elsevier SAS.
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页码：1654 / 1661
页数：8
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