Nearly half of the people suffering from schizophrenia also present with a lifetime history of substance use disorders (SUD), a rate that is much higher than the one seen among unaffected individuals. This phenomenon suggests that the factors influencing SUD risk in schizophrenia may be more numerous and/or complex than those modulating SUD risk in the general population. It is critically important to address this comorbidity because SUD in schizophrenic patients is associated with poorer clinical outcomes and contributes significantly to their morbidity and mortality.
机构:
Yale Sch Med, Dept Psychiat, West Haven, CT 06510 USA
VA CT Healthcare Ctr, West Haven, CT 06516 USAYale Sch Med, Dept Psychiat, West Haven, CT 06510 USA
Polimanti, Renato
Agrawal, Arpana
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机构:
Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63110 USAYale Sch Med, Dept Psychiat, West Haven, CT 06510 USA
Agrawal, Arpana
Gelernter, Joel
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机构:
Yale Sch Med, Dept Psychiat, West Haven, CT 06510 USA
VA CT Healthcare Ctr, West Haven, CT 06516 USA
Yale Sch Med, Dept Genet, New Haven, CT USA
Yale Sch Med, Dept Neurosci, New Haven, CT USAYale Sch Med, Dept Psychiat, West Haven, CT 06510 USA