The introduction of halothane into clinical practice: The Oxford experience

被引：4
|
作者：
O'Brien, H. D. [1 ]
机构：
[1] Prince Wales Hosp, Dept Anaesthet, Sydney, NSW, Australia
来源：
ANAESTHESIA AND INTENSIVE CARE | 2006年 / 34卷
关键词：
anaesthesia; halothane; history; Oxford; Nuffield Department;
D O I：
10.1177/0310057X0603401S03
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
This paper reviews the clinical situation in anaesthesia before the introduction of halothane into clinical practice in 1956, emphasising the limitations of agents available at the time. The background to the development of halogenated hydrocarbon compounds as anaesthesia agents is presented, including the involvement of Imperial Chemical Industries in England. The Nuffield Department of Anaesthetics was involved in the clinical trials and the designing and execution of these. The results of their work and the problems encountered are presented.
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页码：27 / 32
页数：6
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