Distant Recurrence Risk after Late Ipsilateral Breast Tumor Recurrence: Results of a Retrospective, Single-Institution Study

被引:2
|
作者
Ishitobi, Makoto [1 ]
Okuno, Jun [1 ]
Kittaka, Nobuyoshi [1 ]
Nakayama, Takahiro [1 ]
Koyama, Hiroki [1 ]
Tamaki, Yasuhiro [1 ]
机构
[1] Osaka Med Ctr Canc & Cardiovasc Dis, Dept Breast & Endocrine Surg, Osaka 5378511, Japan
关键词
Breast cancer; Ipsilateral breast tumor recurrence; Late recurrence; SURGICAL ADJUVANT BREAST; 20-YEAR FOLLOW-UP; LOCAL RECURRENCE; CONSERVING TREATMENT; PROGNOSTIC-FACTORS; LOCOREGIONAL RECURRENCES; CANCER; THERAPY; IMPACT; MASTECTOMY;
D O I
10.1159/000437440
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Objectives: There is limited information regarding risk factors for distant recurrence in patients with late ipsilateral breast tumor recurrence (IBTR). Methods: Late IBTR was defined as IBTR occurring >5 years after the initial surgery. Seventy-eight patients with late IBTR were reviewed to examine the risk factors of distant recurrence. Results: The negative estrogen receptor and positive HER2 statuses of IBTR were significantly correlated with poorer distant disease-free survival (p = 0.03 and 0.02, respectively). Multivariate analyses demonstrated that the HER2 status of IBTR was an independent predictive factor of distant recurrence (p = 0.04). Conclusions: The results of our retrospective, single-institution study revealed that the HER2 status of IBTR was an independent predictive factor of distant recurrence in patients with late IBTR. (C) 2015 S. Karger AG, Basel
引用
收藏
页码:269 / 274
页数:6
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