Assessment of ocular discomfort caused by 5 shampoos using the Slug Mucosal Irritation test

被引：5
|
作者：
Petit, Jean-Yanique [1 ]
Dore, Vanessa [1 ]
Marignac, Genevieve [1 ]
Perrot, Sebastien [1 ]
机构：
[1] Univ Paris Est, Ecole Natl Vet Alfort, Inst Rech Clin Anim, 7 Ave Gen Gaulle, F-94704 Maisons Alfort, France
来源：
TOXICOLOGY IN VITRO | 2017年 / 40卷
关键词：
Slug Mucosal Irritation test; Ocular discomfort; Veterinary shampoos; RABBIT NASAL-MUCOSA; BENZALKONIUM CHLORIDE; TOXICITY; REMOVAL; POTENCY; SURFACE; TOOL;
D O I：
10.1016/j.tiv.2017.01.002
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
Assessment of ocular discomfort caused by veterinary care products is less legitimately regulated than that caused by human care products. The Slug Mucosal Irritation (SMI) assay was adapted to evaluate canine hygiene shampoos to predict ocular discomfort Experiments were performed using four commercial canine shampoos, a baby care product, and two controls (ArtTear (R) and BAC1%). Groups of 3 slugs were tested with 5% dilution of the 7 test substances. The negative control (ArtTear) was the best tolerated. The baby care product Mixa bebe as well as Douxo Entretien Demelant and Phlox Shampooing Entretien were classified to cause mild ocular discomfort. Together with the positive control (BAC 1%), Shampooing Physiologique Virbac and Physiovet Shampooing were considered to cause severe ocular discomfort. Different intensities of ocular discomfort were measured for veterinary care products. The SMI model was considered as a reproducible and adaptable evaluation method for screening veterinary care products causing ocular discomfort. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：243 / 247
页数：5
相关论文
共 48 条
  • [31] Evaluating the ocular irritation potential of 54 test articles using the epiocular human tissue construct model (OCL-200).
    Blazka, ME
    Harbell, JW
    Klausner, M
    Merrill, JC
    Kubilus, J
    Kloos, C
    Bagley, DM
    TOXICOLOGICAL SCIENCES, 2003, 72 : 221 - 221
  • [32] Study of the difficulties encountered by Brazilian laboratories in implementing alternative methods to animal use: assessment of Ocular Irritation and the Bovine Corneal Opacity and Permeability (BCOP) test
    Gimenes, Izabela
    Presgrave, Octavio Augusto Franca
    Gonzalez, Marcelo Salabert
    Alves, Gutemberg Gomes
    VIGILANCIA SANITARIA EM DEBATE-SOCIEDADE CIENCIA & TECNOLOGIA, 2024, 12
  • [33] A new alternative method to the Draize eye test for the assessment of the eye irritation potential of chemicals by using HCE-T cell
    Cho, S. A.
    An, S.
    Kim, H. K.
    Lee, T. R.
    TOXICOLOGY LETTERS, 2010, 196 : S247 - S248
  • [34] Assessment of groundwater resources potential using geoelectrical method and slug test in Tegal District, Central Java']Java Province, Indonesia
    Wilopo, Wahyu
    Rachman, Moch Hasmannoor
    Putra, Doni Prakasa Eka
    1ST GEOSCIENCES AND ENVIRONMENTAL SCIENCES SYMPOSIUM (ICST 2020), 2020, 200
  • [35] Comparative assessment of the acute skin irritation potential of detergent formulations using a novel human 4-h patch test method
    Robinson, MK
    Kruszewski, FH
    Al-Atrash, J
    Blazka, ME
    Gingell, R
    Heitfeld, FA
    Mallon, D
    Snyder, NK
    Swanson, JE
    Casterton, PL
    FOOD AND CHEMICAL TOXICOLOGY, 2005, 43 (12) : 1703 - 1712
  • [36] Risk Assessment of Twister 5EC Insecticide by using Allium and Ames Test
    Akyil, Dilek
    RESEARCH JOURNAL OF BIOTECHNOLOGY, 2019, 14 (07): : 120 - 125
  • [37] Implementing the Horizontal Vestibular Ocular Reflex Test While Using an Eye-Tracker as an Assessment Tool for Concussions Diagnosis
    Katrahmani, Atefeh
    Romoser, Matthew
    ADVANCES IN NEUROERGONOMICS AND COGNITIVE ENGINEERING, 2019, 775 : 189 - 195
  • [38] Assessment of the levels of damage caused by Fusarium head blight in wheat using an improved YoloV5 method
    Zhang, Dong-Yan
    Luo, Han-Sen
    Wang, Dao-Yong
    Zhou, Xin-Gen
    Li, Wei-Feng
    Gu, Chun-Yan
    Zhang, Gan
    He, Fang-Ming
    COMPUTERS AND ELECTRONICS IN AGRICULTURE, 2022, 198
  • [39] Survey of ocular irritation predictive capacity using Chorioallantoic Membrane Vascular Assay (CAMVA) and Bovine Corneal Opacity and Permeability (BCOP) test historical data for 319 personal care products over fourteen years
    Donahue, D. A.
    Kaufman, L. E.
    Avalos, J.
    Simion, F. A.
    Cerven, D. R.
    TOXICOLOGY IN VITRO, 2011, 25 (02) : 563 - 572
  • [40] Mapping analysis to estimate EQ-5D utility values using the COPD assessment test in Korea
    Jaeok Lim
    Sang-Eun Choi
    Eunmi Bae
    Daewon Kang
    Eun-A Lim
    Gyeong-Seon Shin
    Health and Quality of Life Outcomes, 17
12345