Presynaptic induction and expression of NMDA-dependent LTP

被引:21
|
作者
Paré, D [1 ]
机构
[1] Rutgers State Univ, Ctr Mol & Behav Neurosci, Newark, NJ 07102 USA
关键词
D O I
10.1016/j.tins.2004.05.004
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
It is almost axiomatic in neuroscience that postsynaptically induced NMDA-dependent long-term potentiation (LTP) is a cellular substrate of memory. As a result, memory impairments caused by experimental reductions of NMDA currents are often interpreted as evidence that this form of plasticity is involved in memory formation. However, a recent Nature study indicates that not all NMDA-dependent UP is induced postsynaptically.
引用
收藏
页码:440 / 441
页数:2
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