Transition-metal free reactions of boronic acids: cascade addition - ring-opening of furans towards functionalized γ-ketoaldehydes

被引：11

作者：

Roscales, S. ^{[1
]}

Csaky, A. G. ^{[1
]}

机构：

[1] Univ Complutense, Inst Pluridisciplinar, Campus Excelencia Int Moncloa, E-28040 Madrid, Spain

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 14期

关键词：

BOND-FORMING REACTIONS; CARBOXYLIC-ACIDS; REARRANGEMENT; ARYL; STRATEGY; AMINES;

D O I：

10.1039/c5cc08809g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We describe the first ring-opening of furfuryl alcohols with boronic acids to afford functionalized gamma-ketoaldehydes. The transformation builds a new C-C bond at the original C-4 of the starting furan, and tolerates ring-substitution at C-3 and C-4 positions. The reaction takes place under metal-free conditions by promotion with tartaric acid.

引用

页码：3018 / 3021

页数：4

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