A new data mining tool for analyzing Coumarin-based prodrugs

被引：0
|
作者：
Fang, H [1 ]
Li, J [1 ]
Sun, Y [1 ]
Wang, B [1 ]
Zhang, YQ [1 ]
机构：
[1] Georgia State Univ, Dept Chem, Atlanta, GA 30303 USA
来源：
DATA MINING AND KNOWLEDGE DISCOVERY: THEORY, TOOLS, AND TECHNOLOGY VI | 2004年 / 5433卷
关键词：
neural network; data mining; fuzzy logic; chem-informatics; bioinformatics; drug discovery;
D O I：
10.1117/12.541595
中图分类号：
TP18 [人工智能理论];
学科分类号：
081104 ; 0812 ; 0835 ; 1405 ;
摘要：
This paper focuses on using fuzzy neural data mining techniques to analyze nonlinear relations among chemical factors. Through standardizing and rescaling the raw data, we processed the data into fuzzy neural network not only to learn chemical knowledge from large amounts of experimental data, but also predict future chemical parameters for further experimental verification. The results show that the most relative chemical factor can be obtained by analyzing the experimental errors using fuzzy rules.
引用
收藏
页码：142 / 152
页数：11
相关论文
共 50 条
  • [21] Photophysical and Electrochemiluminescence of Coumarin-Based Oxazaborines
    Mikysek, Tomas
    Nikolaou, Pavlos
    Kafexholli, Mirjeta
    Simunek, Petr
    Vana, Jiri
    Markova, Aneta
    Vala, Martin
    Valenti, Giovanni
    CHEMELECTROCHEM, 2020, 7 (07) : 1550 - 1557
  • [22] A comparison of the bioconversion rates and the Caco-2 cell permeation characteristics of coumarin-based cyclic prodrugs and methylester-based linear prodrugs of RGD peptidomimetics
    Camenisch, GP
    Wang, W
    Wang, BH
    Borchardt, RT
    PHARMACEUTICAL RESEARCH, 1998, 15 (08) : 1174 - 1181
  • [23] A Coumarin-Based Array for the Discrimination of Amyloids
    Trinh, Natalie
    Bhuskute, Kaustubh R.
    Varghese, Nikhil R.
    Buchanan, Jessica A.
    Xu, Yijia
    Mccutcheon, Fiona M.
    Medcalf, Robert L.
    Jolliffe, Katrina A.
    Sunde, Margaret
    New, Elizabeth J.
    Kaur, Amandeep
    ACS SENSORS, 2024, 9 (02) : 615 - 621
  • [24] Coumarin-based emissive liquid crystals
    Buchs, Jens
    Gaebler, Michael
    Janietz, Dietmar
    Sawade, Hans
    LIQUID CRYSTALS, 2014, 41 (11) : 1605 - 1618
  • [25] A Comparison of the Bioconversion Rates and the Caco-2 Cell Permeation Characteristics of Coumarin-Based Cyclic Prodrugs and Methylester-Based Linear Prodrugs of RGD Peptidomimetics
    Gian P. Camenisch
    Wei Wang
    Binghe Wang
    Ronald T. Borchardt
    Pharmaceutical Research, 1998, 15 : 1174 - 1181
  • [26] A New Coumarin-Based Colorimetric and Fluorometric Sensor for Cu2+
    An, Kyoung-Lyong
    Park, Koon Ha
    Jun, Kun
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2014, 35 (07): : 2183 - 2185
  • [27] Reversible Two-Photon Optical Data Storage in Coumarin-Based Copolymers
    Iliopoulos, Konstantinos
    Krupka, Oksana
    Gindre, Denis
    Salle, Marc
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (41) : 14343 - 14345
  • [28] Design and synthesis of a coumarin-based acidichromic colorant
    Lin, Shih-Lun
    Kuo, Pei-Yu
    Yang, Ding-Yah
    MOLECULES, 2007, 12 (07) : 1316 - 1324
  • [29] Synthesis and photochromic properties of coumarin-based dithienylethenes
    Yaqian Li
    Haichuang Lan
    Shuzhang Xiao
    Research on Chemical Intermediates, 2018, 44 : 6489 - 6495
  • [30] Supramolecular Control of the Photoisomerization of a Coumarin-Based Photoswitch
    Kiss, Etelka
    Mester, David
    Bojtar, Marton
    Miskolczy, Zsombor
    Biczok, Laszlo
    Hessz, Dora
    Kallay, Mihaly
    Kubinyi, Miklos
    ACS OMEGA, 2024, 9 (52): : 51652 - 51664
12345